ArticleLung2024
Longitudinal Cough Frequency Monitoring in Persistent Coughers: Daily Variability and Predictability.
Article in Lung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07212439 (Continuous Cough Monitoring for Early Detection of COPD Exacerbations Using Hyfe), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Continuous Cough Monitoring for Early Detection of COPD Exacerbations Using Hyfe
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cough biomarkers for diagnosis and monitoring of respiratory disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Cough hypersensitivity risk increases during heatwaves and can be reduced by inhalation of alkaline aerosols of endogenous ions.Scientific reports · 2026Article
- Cough in Interstitial Lung Disease: Current Knowledge and Research Gaps.Pulmonary therapy · 2026Review
- Endpoints in cough studies: learnings from the ERS Cough Conference.ERJ open research · 2026Article
- Biomechanical Behavior of an Aged Synthetic Hernia Mesh Under a Cough-Simulating Protocol.Materials (Basel, Switzerland) · 2026Article
- Article
- Prospective study to evaluate the effectiveness of guideline-based therapy for chronic cough and refractory chronic cough: PROCOUGH.ERJ open research · 2026Article
- Converting a Cough Counter into a Cough Monitor: A Way Forward?Medical sciences (Basel, Switzerland) · 2026Review
- Observational
- Evaluating smartphone-based cough frequency monitoring for tuberculosis screening and triage in Uganda: A mixed-methods evaluation.PLOS global public health · 2026Article
- The value of continuous cough monitoring: a narrative review.Journal of thoracic disease · 2025Review
- Heat waves elevate risks of airway hypersensitivity that inhaled endogenous ions reduce.Research square · 2025Article
- Assessment of cough in asthma patients attending clinic using the cough questionnaire for asthma (CQA).Journal of thoracic disease · 2025Article
- Improved Precision of COPD Exacerbation Detection in Night-Time Cough Monitoring.Journal of personalized medicine · 2025Article
- Efficacy and safety of flupentixol-melitracen in patients with refractory chronic cough: a randomised, double-blinded, placebo-controlled clinical trial.EClinicalMedicine · 2025Article
- Which Patients with COPD Would Benefit from Cough Monitoring?Journal of clinical medicine · 2025Article
- The Effect of Attentional Manipulation on Cough Reflex Sensitivity in Individuals with Refractory Chronic Cough and Healthy Controls.Journal of clinical medicine · 2025Article
- LUNG Year in Review: 2024.Lung · 2025Article
- Nighttime Cough Characteristics in Chronic Obstructive Pulmonary Disease Patients.Sensors (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe determined the cough counts and their variability in subjects with persistent cough for 30 days.
methodsThe Hyfe cough tracker app uses the mobile phone microphone to monitor sounds and recognizes cough with artificial intelligence-enabled algorithms. We analyzed the daily cough counts including the daily predictability rates of 97 individuals who monitored their coughs over 30 days and had a daily cough rate of at least 5 coughs per hour.
resultsThe mean (median) daily cough rates varied from 6.5 to 182 (6.2 to 160) coughs per hour, with standard deviations (interquartile ranges) varying from 0.99 to 124 (1.30 to 207) coughs per hour among all subjects. There was a positive association between cough rate and variability, as subjects with higher mean cough rates (OLS) have larger standard deviations. The accuracy of any given day for predicting all 30 days is the One Day Predictability for that day, defined as the percentage of days when cough frequencies fall within that day's 95% confidence interval. Overall Predictability was the mean of the 30-One Day Predictability percentages and ranged from 95% (best predictability) to 30% (least predictability).
conclusionThere is substantial within-day and day-to-day variability for each subject with persistent cough recorded over 30 days. If confirmed in future studies, the clinical significance and the impact on the use of cough counts as a primary end-point of cough interventions of this variability need to be assessed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.