Evidence map›Paper›PMID 39085407›Full record

ReviewActa pharmacologica Sinica2024

Immunocyte membrane-derived biomimetic nano-drug delivery system: a pioneering platform for tumour immunotherapy.

Yuan-Ye Zeng, Qing Gu, Dan Li, Ai-Xue Li, Rong-Mei Liu, Jian-Ying Liang, Ji-Yong Liu

Abstract readReview
In one paragraph

Review in Acta pharmacologica Sinica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuan-Ye Zeng *School of Pharmacy, Fudan University, Shanghai, 201203, China.
Qing Gu *Department of Pharmacy, Jingan District Zhabei Central Hospital, Shanghai, 200070, China.
Dan Li *Department of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Ai-Xue LiDepartment of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Rong-Mei LiuDepartment of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Jian-Ying LiangSchool of Pharmacy, Fudan University, Shanghai, 201203, China. jyliang@shmu.edu.cn.
Ji-Yong LiuDepartment of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. liujiyong@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor immunotherapy characterized by its high specificity and minimal side effects has achieved revolutionary progress in the field of cancer treatment. However, the complex mechanisms of tumor immune microenvironment (TIME) and the individual variability of patients' immune system still present significant challenges to its clinical application. Immunocyte membrane-coated nanocarrier systems, as an innovative biomimetic drug delivery platform, exhibit remarkable advantages in tumor immunotherapy due to their high targeting capability, good biocompatibility and low immunogenicity. In this review we summarize the latest research advances in biomimetic delivery systems based on immune cells for tumor immunotherapy. We outline the existing methods of tumor immunotherapy including immune checkpoint therapy, adoptive cell transfer therapy and cancer vaccines etc. with a focus on the application of various immunocyte membranes in tumor immunotherapy and their prospects and challenges in drug delivery and immune modulation. We look forward to further exploring the application of biomimetic delivery systems based on immunocyte membrane-coated nanoparticles, aiming to provide a new framework for the clinical treatment of tumor immunity.

Indexed as

Biomimetic MaterialsImmunotherapyNeoplasmsAnimalsBiomimeticsCancer VaccinesCell MembraneDrug Delivery SystemsHumansNanoparticle Drug Delivery SystemNanoparticlesTumor MicroenvironmentCancer VaccinesNanoparticle Drug Delivery Systembiomimetic nanoparticlesdrug deliveryimmunocyte membranetumour immunotherapy

Identifiers

PMID39085407
PMCPMC11579519

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.