Evidence map›Paper›PMID 39085354›Full record

ArticleExperimental & molecular medicine2024

Astrocytic 5-HT

Qian-Yun Wu, Lian-Hong Lin, Kun Lu, Si-Fu Deng, Wei-Min Li, Yuan Xu, Bin Zhang, Ji-Hong Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental & molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian-Yun Wu *Department of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Lian-Hong Lin *Department of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Kun Lu *Department of Pediatric Orthopaedic, Zhengzhou Orthopaedics Hospital, Zhengzhou, 450052, China.
Si-Fu DengDepartment of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Wei-Min LiDepartment of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Yuan XuDepartment of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Bin ZhangDepartment of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. zhang73bin@hotmail.com.
Ji-Hong LiuDepartment of Psychiatry, Institute of Brain Disease, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. weiliu1029@smu.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 8207051451, 82271525
6 · The paper itself

Abstract

NMDA receptor-dependent long-term depression (LTD) in the hippocampus is a well-known form of synaptic plasticity that has been linked to different cognitive functions. Although the underlying mechanisms remain unclear, this form of LTD cannot be induced by low-frequency stimulation (LFS) in adult mice. In this study, we found that LFS-induced LTD was not easily induced in adult animals and was age dependent. Interestingly, the level of the 5-HT

Indexed as

AstrocytesFearHippocampusLong-Term Synaptic DepressionMemoryReceptor, Serotonin, 5-HT1AAgingAnimalsExtinction, PsychologicalMaleMiceMice, Inbred C57BLMice, KnockoutSynaptic TransmissionHtr1a protein, mouseReceptor, Serotonin, 5-HT1A

Identifiers

PMID39085354
PMCPMC11371825

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.