Evidence map›Paper›PMID 39085312›Full record

ArticleScientific reports2024

A new model for determining risk of male infertility from serum hormone levels, without semen analysis.

Hideyuki Kobayashi, Masato Uetani, Fumito Yamabe, Yozo Mitsui, Koichi Nakajima, Koichi Nagao

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Unravelling male infertility through epigenetics: present understanding and future challenges.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hideyuki KobayashiDepartment of Urology, Toho University School of Medicine, 6-11-1, Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan. hideyukk@med.toho-u.ac.jp.
Masato UetaniDepartment of Urology, Toho University School of Medicine, 6-11-1, Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
Fumito YamabeDepartment of Urology, Toho University School of Medicine, 6-11-1, Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
Yozo MitsuiDepartment of Urology, Toho University School of Medicine, 6-11-1, Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
Koichi NakajimaDepartment of Urology, Toho University School of Medicine, 6-11-1, Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
Koichi NagaoDepartment of Urology, Toho University School of Medicine, 6-11-1, Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated a screening method using only serum hormone levels and AI (artificial intelligence) predictive analysis. Among 3662 patients, numbers for NOA (non-obstructive azoospermia), OA (obstructive azoospermia), cryptozoospermia, oligozoospermia and/or asthenozoospermia, normal, and ejaculation disorder were 448, 210, 46, 1619, 1333, and 6, respectively. "Normal" was defined as semen findings normal according to the WHO (World Health Organization) Manual for Human Semen Testing of 2021. We extracted age, LH (luteinizing hormone), FSH (follicle stimulating hormone), PRL (prolactin), testosterone, E2 (estradiol), and T (testosterone)/E2 from medical records. A total motility sperm count of 9.408 × 10

Indexed as

Infertility, MaleLuteinizing HormoneSemen AnalysisAdultArtificial IntelligenceAzoospermiaEstradiolFollicle Stimulating HormoneHumansMaleMiddle AgedProlactinROC CurveTestosteroneEstradiolFollicle Stimulating HormoneLuteinizing HormoneProlactinTestosteroneArtificial intelligenceHormonal evaluationMachine learningMale infertilitySemen analysis

Identifiers

PMID39085312
PMCPMC11291977

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.