Evidence map›Paper›PMID 39085207›Full record

ArticleNature communications2024

The parasitic lifestyle of an archaeal symbiont.

Joshua N Hamm, Yan Liao, Andriko von Kügelgen, Nina Dombrowski, Evan Landers, Christopher Brownlee, Emma M V Johansson, Renee M Whan, Matthew A B Baker, Buzz Baum and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. DPANN symbiont ofiScience · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Joshua N Hamm *School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia. josh.n.hamm@gmail.com.ORCID 0000-0001-7395-6562
Yan Liao *Australian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, NSW, 2007, Australia.ORCID 0000-0002-8492-2648
Andriko von KügelgenStructural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.ORCID 0000-0002-0017-2414
Nina DombrowskiDepartment of Marine Microbiology and Biogeochemistry, Royal Netherlands Institute for Sea Research, Den Hoorn, The Netherlands, 1797 SZ.ORCID 0000-0003-1917-2577
Evan LandersSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Christopher BrownleeBiological Resources Imaging Laboratory, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, NSW, 2052, Australia.
Emma M V JohanssonBiological Resources Imaging Laboratory, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, NSW, 2052, Australia.
Renee M WhanKatharina Gaus Light Microscopy Facility, Mark Wainwright Analytical Centre, The University of New South Wales, Sydney, NSW, 2052, Australia.
Matthew A B BakerSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0002-5839-6904
Buzz BaumCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.ORCID 0000-0002-9201-6186
Tanmay A M BharatStructural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.ORCID 0000-0002-0168-0277
Iain G DugginAustralian Institute for Microbiology and Infection, University of Technology Sydney, Ultimo, NSW, 2007, Australia.ORCID 0000-0003-4868-7350
Anja SpangDepartment of Marine Microbiology and Biogeochemistry, Royal Netherlands Institute for Sea Research, Den Hoorn, The Netherlands, 1797 SZ.ORCID 0000-0002-6518-8556
Ricardo CavicchioliSchool of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0001-8989-6402

Funding

Medical Research Council MC_UP_1201/31
6 · The paper itself

Abstract

DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology.

Indexed as

HalorubrumSymbiosisArchaeaGenome, ArchaealNanoarchaeotaPhylogeny

Identifiers

PMID39085207
PMCPMC11291902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.