Evidence map›Paper›PMID 39084754›Full record

ReviewAdvances in kidney disease and health2024

Collapsing Glomerulopathy.

Abbal Koirala, Shreeram Akilesh, J Ashley Jefferson

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in kidney disease and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abbal KoiralaDivision of Nephrology, University of Washington, Seattle, Washington.
Shreeram AkileshDepartment of Pathology, University of Washington, Seattle, Washington.
J Ashley JeffersonDivision of Nephrology, University of Washington, Seattle, Washington. Electronic address: jashleyj@uw.edu.

Funding

Mechanisms of Kidney Injury in COVID-19R01DK130386 · NIDDK · UNIVERSITY OF WASHINGTON · PI AKILESH, SHREERAM, FREEDMAN, BENJAMIN SOLOMON · 2021 to 2023
$1.2M
NIDDK NIH HHS R01 DK130386
6 · The paper itself

Abstract

Collapsing glomerulopathy (CG) is a pattern of kidney injury characterized by segmental or global collapse of the glomerular tuft associated with overlying epithelial cell hyperplasia. Although CG may be idiopathic, a wide range of etiologies have been identified that can lead to this pattern of injury. Recent advances have highlighted the role of inflammatory and interferon signaling pathways and upregulation of apolipoprotein L1 (APOL1) within podocytes in those carrying a high-risk APOL1 genotype. In this review, we describe the etiology, pathogenesis, pathology, and clinical course of CG, focusing on nonviral etiologies. We also describe current treatments and explore potential therapeutic options targeting interferon/APOL1 pathways in CG.

Indexed as

Apolipoprotein L1ApolipoproteinsHumansKidney GlomerulusPodocytesSignal TransductionAPOL1 protein, humanApolipoprotein L1ApolipoproteinsAPOL1Collapsing glomerulopathyFocal segmental glomerulosclerosisInterferonNephrotic syndromePodocyte

Identifiers

PMID39084754
PMCPMC11296495

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.