Evidence map›Paper›PMID 39084716›Full record

ReviewCardiac electrophysiology clinics2024

Cardiac Neuroanatomy and Fundamentals of Neurocardiology.

Peter Hanna, Jeffrey L Ardell

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiac electrophysiology clinics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter HannaUniversity of California Los Angeles (UCLA) Cardiac Arrhythmia Center, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA; UCLA Neurocardiology Research Program of Excellence, UCLA, Los Angeles, CA 90095, USA.
Jeffrey L ArdellUniversity of California Los Angeles (UCLA) Cardiac Arrhythmia Center, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA; UCLA Neurocardiology Research Program of Excellence, UCLA, Los Angeles, CA 90095, USA. Electronic address: jardell@mednet.UCLA.edu.

Funding

Neural Control of Myocardial Excitability at the Nerve Myocyte InterfaceP01HL164311 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Olujimi A Ajijola · 2023 to 2026
$11.3M
Bioelectric monitoring and neuromodulation of the heartR01HL162921 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALYANAM SHIVKUMAR, Corey B Smith · 2023 to 2026
$3.4M
Investigation of Partial Electrical Nerve Block for Autonomic RegulationR01HL150136 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI VRABEC, TINA LOUISE · 2020 to 2024
$2.2M
American Heart Association-American Stroke Association 23CDA1039446NHLBI NIH HHS P01 HL164311NHLBI NIH HHS R01 HL150136NHLBI NIH HHS R01 HL162921
6 · The paper itself

Abstract

Cardiac control is mediated via nested-feedback reflex control networks involving the intrinsic cardiac ganglia, intra-thoracic extra-cardiac ganglia, spinal cord, brainstem, and higher centers. This control system is optimized to respond to normal physiologic stressors; however, it can be catastrophically disrupted by pathologic events such as myocardial ischemia. In fact, it is now recognized that cardiac disease progression reflects the dynamic interplay between adverse remodeling of the cardiac substrate coupled with autonomic dysregulation. With advances in understanding of this network dynamic in normal and pathologic states, neuroscience-based neuromodulation therapies can be devised for the management of acute and chronic cardiac pathologies.

Indexed as

HeartAutonomic Nervous SystemHeart DiseasesHumansAutonomic nervous systemCardiac innervationNeurocardiologyNeuromodulation

Identifiers

PMID39084716
PMCPMC12767264

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.