Evidence map›Paper›PMID 39084661›Full record

ArticlePhysics in medicine and biology2024

Commissioning an ultra-high-dose-rate electron linac with end-to-end tests.

Tianyuan Dai, Austin M Sloop, Muhammad R Ashraf, Jacob P Sunnerberg, Megan A Clark, Petr Bruza, Brian W Pogue, Lesley Jarvis, David J Gladstone, Rongxiao Zhang

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Using hydrated electron temporal measurement as dosimetry of individual electron FLASH beam pulses.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tianyuan DaiThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.ORCID 0009-0005-5493-6933
Austin M SloopThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.
Muhammad R AshrafStanford Radiation Oncology, Palo Alto, CA 94304, United States of America.
Jacob P SunnerbergThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.ORCID 0000-0001-7779-6447
Megan A ClarkThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.
Petr BruzaThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.ORCID 0000-0002-6196-5872
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.ORCID 0000-0002-9887-670X
Lesley JarvisDepartment of Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, United States of America.
David J GladstoneThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.
Rongxiao ZhangThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Optimization of MeV FLASH radiotherapy for normal tissue preservationU01CA260446 · NCI · DARTMOUTH COLLEGE · PI David J. Gladstone, Jack Hoopes · 2022 to 2026
$3.1M
Novel Optimization Methods and Treatment Planning System for Clinically-Deliverable Truly-Hybrid Proton-Photon RadiotherapyR37CA250921 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Hao Gao · 2021 to 2026
$2.2M
Ultra-fast imaging for the safe delivery of electron FLASH radiation therapyR44CA268466 · NCI · DOSEOPTICS, LLC · PI BRUZA, PETR · 2022 to 2023
$2.0M
Simultaneous dose and dose rate optimization for clinical FLASH proton radiotherapyR01CA261964 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GAO, HAO · 2022 to 2025
$2.0M
Training in Surgical InnovationT32EB021966 · NIBIB · DARTMOUTH COLLEGE · PI Eric R Fossum, Sohail K Mirza · 2017 to 2026
$1.7M
Treatment Planning System for Electron FLASH radiation therapyR21CA277420 · NCI · UNIVERSITY OF MISSOURI-COLUMBIA · PI ZHANG, RONGXIAO · 2024 to 2025
$438k
NCI NIH HHS P30 CA023108NCI NIH HHS R01 CA261964NCI NIH HHS R21 CA277420NCI NIH HHS R37 CA250921NCI NIH HHS R44 CA268466NCI NIH HHS U01 CA260446NIBIB NIH HHS T32 EB021966
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ElectronsParticle AcceleratorsPhantoms, ImagingRadiotherapy DosageAnimalsMiceMonte Carlo MethodRadiation Dosagecommissioningelectronend-to-end testFLASHMobetronultra-high dose rate

Identifiers

PMID39084661
PMCPMC12152580

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.