Evidence map›Paper›PMID 39084517›Full record

Observational studyChest2025

The Use of a Tailored Decision Aid to Improve Understanding of Lung Cancer Screening in People With HIV.

Nicholas R Murphy, Kristina Crothers, Madison Snidarich, Jehan Z Budak, Meagan C Brown, Bryan J Weiner, Nicholas Giustini, Tanner Caverly, Katherine Durette, Katie DeCell and 1 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Chest, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04682301 (Tailoring Shared Decision Making for Lung Cancer Screening in Persons With HIV), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04682301 completednot on this map

Tailoring Shared Decision Making for Lung Cancer Screening in Persons With HIV (PWH)

TypeobservationalSponsorFred Hutchinson Cancer CenterRan2021 to 2023Enrolled102ConditionsLung CarcinomaArmsBehavioral Intervention, Discussion (focus group), Discussion (feedback on SDM), Interview, Survey Administration
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Updates in Lung Cancer Screening: A Decade of Evidence.Seminars in respiratory and critical care medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicholas R MurphyDivision of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA. Electronic address: nrmurphy@uw.edu.
Kristina CrothersDivision of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA; Veterans Affairs Puget Sound Healthcare System, Seattle, WA.
Madison SnidarichDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA.
Jehan Z BudakDivision of Allergy and Infectious Diseases, University of Washington, Seattle, WA.
Meagan C BrownDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA; Kaiser Permanente Washington Health Research Institute, Seattle, WA; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA.
Bryan J WeinerDepartment of Global Health, University of Washington School of Public Health, Seattle, WA; Department of Health Services, University of Washington School of Public Health, Seattle, WA.
Nicholas GiustiniDivision of Hematology & Oncology, Department of Medicine, University of Washington, Seattle, WA.
Tanner CaverlyDepartment of Learning Health Sciences, University of Michigan, Ann Arbor VA Center for Clinical Management Research, Ann Arbor, MI.
Katherine DuretteFred Hutchinson Cancer Center, Seattle, WA; Division of Hematology and Oncology, University of Washington School of Medicine, Seattle, WA.
Katie DeCellFred Hutchinson Cancer Center, Seattle, WA; Division of Hematology and Oncology, University of Washington School of Medicine, Seattle, WA.
Matthew TripletteDivision of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
NCI NIH HHS P30 CA015704NHLBI NIH HHS T32 HL007287
6 · The paper itself

Abstract

backgroundPeople with HIV are at increased risk for lung cancer and multimorbidity, complicating the balance of risks and benefits of lung cancer screening. We previously adapted Decision Precision (screenlc.com) to guide shared decision-making for lung cancer screening in people with HIV. RESEARCH QUESTION: Does an HIV-adapted and personally tailored decision aid improve shared decision-making regarding lung cancer screening in people with HIV as measured by knowledge, decisional conflict, and acceptability? STUDY DESIGN AND

methodsThis was a single-arm pilot trial of the decision aid in 40 participants with HIV eligible for lung cancer screening. The decision aid included personalized screening recommendations and HIV-specific, 5-year risk estimates of lung cancer and all-cause mortality. Participants reviewed the decision aid at shared decision-making visits and completed previsit and postvisit surveys with measures of knowledge about lung cancer screening, acceptability, and decisional conflict.

resultsThe 40 enrolled participants were a median age of 62 years, 60% currently smoked, and they had median 5-year risks of lung cancer and all-cause mortality of 2.0% (IQR, 1.4%-3.3%) and 4.1% (IQR, 3.3%-7.9%), respectively. Personalized recommendations included "Encourage Screening" for 53% of participants and "Preference Sensitive" recommendations for the remainder. Participants showed improvement in two validated knowledge measures with relative improvement of 60% (P < 0.001) on the 12-question lung cancer screening knowledge test and 27% (P < .001) on the seven-question lung cancer screening knowledge score, with significant improvement on questions regarding false-positive and false-negative findings, incidental findings, lung cancer-specific mortality benefit, and the possible harms of screening. Participants reported low scores on the decisional conflict scale (median score, 0; interquartile range, 0-5) and high acceptability. Ninety percent of patients ultimately underwent screening within 1 month of the visit.

interpretationIn our study, this HIV-adapted and personally tailored decision aid improved participants' knowledge of risks, benefits, and characteristics of screening with low decisional conflict and high acceptability. Our results indicate that this decision aid can enable high-quality shared decision-making in this high-risk population. CLINICAL

trial registrationClinicalTrials.gov; No.: NCT04682301; URL: www. CLINICALTRIALS: gov.

Indexed as

Decision Making, SharedDecision Support TechniquesEarly Detection of CancerHIV InfectionsLung NeoplasmsAgedFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPilot ProjectsRisk AssessmentHIVlung cancer screeningshared decision-makingtobacco

Identifiers

PMID39084517
PMCPMC11752131

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.