Evidence map›Paper›PMID 39083801›Full record

ArticleInteractive journal of medical research2024

Consequences of Data Loss on Clinical Decision-Making in Continuous Glucose Monitoring: Retrospective Cohort Study.

Niala den Braber, Carlijn I R Braem, Miriam M R Vollenbroek-Hutten, Hermie J Hermens, Thomas Urgert, Utku S Yavuz, Peter H Veltink, Gozewijn D Laverman

Registry-linked trialAbstract read
In one paragraph

Article in Interactive journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05584293 (DIABASE; Diabetes Mellitus Registry in Second Care), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05584293 recruitingnot on this map

DIABASE; Diabetes Mellitus Registry in Second Care

Typeobservational_patient_registrySponsorZiekenhuisgroep TwenteRan2020 to 2060Enrolled1,500ConditionsDiabetes Mellitus
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Niala den Braber *Biomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0002-9098-3439
Carlijn I R Braem *Biomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0003-2900-9861
Miriam M R Vollenbroek-HuttenBiomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0001-8730-1487
Hermie J HermensBiomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0002-3065-3876
Thomas UrgertBiomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0003-4690-7479
Utku S YavuzBiomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0002-6968-8064
Peter H VeltinkBiomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0002-1796-9999
Gozewijn D LavermanBiomedical Signal and Systems, Faculty of Electrical Engineering, Mathematics And Computer Science, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0002-8716-7115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of missing data on individual continuous glucose monitoring (CGM) data is unknown but can influence clinical decision-making for patients.

objectiveWe aimed to investigate the consequences of data loss on glucose metrics in individual patient recordings from continuous glucose monitors and assess its implications on clinical decision-making.

methodsThe CGM data were collected from patients with type 1 and 2 diabetes using the FreeStyle Libre sensor (Abbott Diabetes Care). We selected 7-28 days of 24 hours of continuous data without any missing values from each individual patient. To mimic real-world data loss, missing data ranging from 5% to 50% were introduced into the data set. From this modified data set, clinical metrics including time below range (TBR), TBR level 2 (TBR2), and other common glucose metrics were calculated in the data sets with and that without data loss. Recordings in which glucose metrics deviated relevantly due to data loss, as determined by clinical experts, were defined as expert panel boundary error (ε

resultsA total of 84 patients contributed to 798 recordings over 28 days. With 5%-50% data loss for 7-28 days recordings, the ε

conclusionsWith a maximum of 30% data loss in 14-day CGM recordings, there is minimal impact of missing data on the clinical interpretation of various glucose metrics.

trial registrationClinicalTrials.gov NCT05584293; https://clinicaltrials.gov/study/NCT05584293.

Indexed as

clinical decision-makingclinical practiceclinical targetscontinuous glucose monitoringcontinuous glucose monitoring metricsdata analysisdata interpretationdata lossdata sciencedecision-makingdecision supportdiabetesdiabetes mellitusdiabeticglucosemetricsmissing datamissing valuesTBRtime below range

Identifiers

PMID39083801
PMCPMC11325125

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.