ArticleScience advances2024
Space is a latent sequence: A theory of the hippocampus.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Inferential planning in the frontal cortex.Cell reports · 2026Article
- Discovering interpretable drug formulation behavior patterns via a mechanistic-augmented conditional variational autoencoder.Scientific reports · 2026Article
- Hippocampal place cells map terrain geometry independently of behavior.Science advances · 2026Article
- The hippocampus as a small-world cognitive map.bioRxiv : the preprint server for biology · 2026Article
- Building Goal-Directed Cognitive Graphs.bioRxiv : the preprint server for biology · 2026Article
- Spaces and sequences in the hippocampus: a homological perspective.Journal of computational neuroscience · 2026Article
- A Rosetta Stone hypothesis for neurophenomenology: mathematical predictions from predictive processing.Neuroscience of consciousness · 2026Article
- Neural sampling from cognitive maps enables goal-directed imagination and planning.Nature machine intelligence · 2026Article
- REMI: Reconstructing Episodic Memory During Internally Driven Path Planning.bioRxiv : the preprint server for biology · 2025Article
- Three types of remapping with linear decoders: A population-geometric perspective.PLoS computational biology · 2025Article
- Three types of remapping with linear decoders: a population-geometric perspective.bioRxiv : the preprint server for biology · 2025Article
- Learning predictive signals within a local recurrent circuit.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories.eLife · 2025Article
- Article
- A hierarchical active inference model of spatial alternation tasks and the hippocampal-prefrontal circuit.Nature communications · 2024Article
- The Algorithmic Agent Perspective and Computational Neuropsychiatry: From Etiology to Advanced Therapy in Major Depressive Disorder.Entropy (Basel, Switzerland) · 2024Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fascinating phenomena such as landmark vector cells and splitter cells are frequently discovered in the hippocampus. Without a unifying principle, each experiment seemingly uncovers new anomalies or coding types. Here, we provide a unifying principle that the mental representation of space is an emergent property of latent higher-order sequence learning. Treating space as a sequence resolves numerous phenomena and suggests that the place field mapping methodology that interprets sequential neuronal responses in Euclidean terms might itself be a source of anomalies. Our model, clone-structured causal graph (CSCG), employs higher-order graph scaffolding to learn latent representations by mapping aliased egocentric sensory inputs to unique contexts. Learning to compress sequential and episodic experiences using CSCGs yields allocentric cognitive maps that are suitable for planning, introspection, consolidation, and abstraction. By explicating the role of Euclidean place field mapping and demonstrating how latent sequential representations unify myriad observed phenomena, our work positions the hippocampus in a sequence-centric paradigm, challenging the prevailing space-centric view.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.