Evidence map›Paper›PMID 39083440›Full record

ArticleACS applied materials & interfaces2024

Unilateral Administration of Surface-Modified G1 and G4 PAMAM Dendrimers in Healthy Mice to Assess Dendrimer Migration in the Brain.

Bhairavi Srinageshwar, Cassandra Thompson, Paulina Otero, Darren T Story, Anna E Wedster, Bethany MacDonald, Nikolas Munro, Sindhuja Koneru, Riley Crandall, Douglas Swanson and 3 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bhairavi SrinageshwarCollege of Medicine, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Cassandra ThompsonProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Paulina OteroProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Darren T StoryProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Anna E WedsterProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Bethany MacDonaldProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Nikolas MunroProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Sindhuja KoneruProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Riley CrandallProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Douglas SwansonDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Ajit SharmaDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Gary L DunbarProgram of Neuroscience, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Julien RossignolCollege of Medicine, Central Michigan University, Mount Pleasant, Michigan 48859, United States.ORCID 0000-0002-8662-0547

Funding

Targeted Circuit Manipulation for Ameliorating Huntington's Disease PathogenesisR21NS132089 · NINDS · CENTRAL MICHIGAN UNIVERSITY · PI HOCHGESCHWENDER, UTE H, ROSSIGNOL, JULIEN · 2023 to 2024
$403k
NINDS NIH HHS R21 NS132089
6 · The paper itself

Abstract

Polyamidoamine (PAMAM) dendrimers are nanoparticles that have a wide scope in the field of biomedicine. Previous evidence shows that the generation 4 (G4) dendrimers with a 100% amine surface (G4-NH

Indexed as

DendrimersAnimalsBrainMaleMiceSurface PropertiesDendrimersPAMAM Starburstbrain clearancecellular uptakedendrimer transportmigrationnanoparticlePAMAM dendrimers

Identifiers

PMID39083440
PMCPMC11331434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.