Evidence map›Paper›PMID 39083355›Full record

ArticleMolecular biology of the cell2024

Shared and redundant proteins coordinate signal cross-talk between MAPK pathways in yeast.

Shu Zhang, Hao Wang, Emily L Sipko, Shuang Li, Timothy A Daugird, Wesley R Legant, Henrik G Dohlman

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. HOG Signaling: A Multifunctional Regulator of Stress Homeostasis inJournal of fungi (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shu ZhangDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-0185-4126
Hao WangDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Emily L SipkoDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Shuang LiDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Timothy A DaugirdDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Wesley R LegantDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Henrik G DohlmanDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

Funding

Negative and positive feedback in cell signalingR35GM118105 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Henrik G. Dohlman · 2016 to 2026
$6.6M
MOLECULAR AND CELLULAR BIOPHYSICS TRAINING PROGRAMT32GM008570 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KUHLMAN, BRIAN A, SLEP, KEVIN C · 1995 to 2022
$5.1M
Connecting the dots between single molecule dynamics and cell differentiationDP2GM136653 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEGANT, WESLEY R. · 2019 to 2019
$2.3M
NIGMS NIH HHS DP2 GM136653NIGMS NIH HHS R35 GM118105NIGMS NIH HHS T32 GM008570
6 · The paper itself

Abstract

All cells must detect, interpret, and adapt to multiple and concurrent stimuli. While signaling pathways are highly specialized, different pathways often share components or have components with overlapping functions. In the yeast

Indexed as

MAP Kinase Signaling SystemMitogen-Activated Protein KinasesOsmotic PressurePheromonesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsGene Expression Regulation, FungalGlycerolIntracellular Signaling Peptides and ProteinsMembrane ProteinsPhosphorylationProtein KinasesFUS3 protein, S cerevisiaeGlycerolHOG1 protein, S cerevisiaeIntracellular Signaling Peptides and ProteinsKSS1 protein, S cerevisiaeMembrane ProteinsMitogen-Activated Protein KinasesPheromonesProtein KinasesSaccharomyces cerevisiae ProteinsSHO1 protein, S cerevisiaeSLN1 protein, S cerevisiae

Identifiers

PMID39083355
PMCPMC11481699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.