Evidence map›Paper›PMID 39083089›Full record

GuidelineEuropean radiology2025

The role of the radiologist in the evaluation of male infertility: recommendations of the European Society of Urogenital Radiology-Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for scrotal imaging.

Francesco Lotti, Michal Studniarek, Cristina Balasa, Jane Belfield, Pieter De Visschere, Simon Freeman, Oliwia Kozak, Karolina Markiet, Subramaniyan Ramanathan, Jonathan Richenberg and 5 more

Abstract readPractice GuidelineReview
In one paragraph

Guideline in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Recent Trends in the Management of Varicocele.Journal of clinical medicine · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Beyond the Basics: Best Practices in Scrotal Ultrasound for the Infertile Male.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Francesco LottiDepartment of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy. francesco.lotti@unifi.it.ORCID http://orcid.org/0000-0001-8343-1807
Michal StudniarekDepartment of Radiology, Medical University of Gdańsk, Gdańsk, Poland.
Cristina BalasaHôpitaux Paris Sud, Service de Radiologie Diagnostique et Interventionnelle, site Bicêtre, 94270, Le Kremlin Bicêtre, France.
Jane BelfieldDepartment of Radiology, Royal Liverpool University Hospital, Liverpool, UK.
Pieter De VisschereDepartment of Radiology and Nuclear Medicine, Ghent University Hospital, Ghent, Belgium.
Simon FreemanUniversity Hospitals Plymouth NHS Trust, Derriford Hospital, Derriford Road, Crownhill, Plymouth, Devon, PL6 8DH, UK.
Oliwia KozakDepartment of Radiology, Medical University of Gdańsk, Gdańsk, Poland.
Karolina MarkietDepartment of Radiology, Medical University of Gdańsk, Gdańsk, Poland.
Subramaniyan RamanathanDepartment of Radiology, Al-Wakra Hospital, Hamad Medical Corporation, PO Box 82228, Doha, Qatar.
Jonathan RichenbergDepartment of Imaging, Brighton and Sussex University Hospitals NHS Trust and Brighton and Sussex Medical School, Brighton, UK.
Mustafa SecilDepartment of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Katarzyna SkrobiszDepartment of Radiology, Medical University of Gdańsk, Gdańsk, Poland.
Athina C TsiliDepartment of Clinical Radiology, School of Health Sciences, Faculty of Medicine, University of Ioannina, 45110, Ioannina, Greece.
Michele Bertolotto *Department of Radiology, University of Trieste, Ospedale di Cattinara, Trieste, Italy.
Laurence Rocher *Hôpital Antoine Béclère, Service de Radiologie, APHP, 157 rue de la Porte de Trivaux, 92140, Clamart, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe Scrotal and Penile Imaging Working Group (SPIWG) of the European Society of Urogenital Radiology (ESUR) aimed to produce recommendations on the role of the radiologist in the evaluation of male infertility focused on scrotal imaging.

methodsThe authors independently performed an extensive literature Medline search and a review of the clinical practice and consensus opinion of experts in the field.

resultsScrotal ultrasound (US) is useful in investigating male infertility. US abnormalities related to abnormal sperm parameters (sperm concentration, total count, motility, and morphology) are low testicular volume (TV), testicular inhomogeneity (TI), cryptorchidism, testicular microlithiasis (TML), high-grade varicocele, bilateral absence of vas deferens, bilateral dilation and echotexture abnormalities of the epididymis. The proposed ESUR-SPIWG recommendations for imaging in the evaluation of male infertility are therefore: to measure TV; investigate TI; perform annual (US) follow-ups up to age 55 in men with a history of cryptorchidism/orchidopexy and/or in men with TML plus "additional risk factors" or with "starry sky" TML; perform scrotal/inguinal US in men with nonpalpable testis; perform scrotal US in men with abnormal sperm parameters to investigate lesions suggestive of tumors; evaluate varicocele in a standardized way; evaluate the presence or absence of vas deferens; investigate the epididymis to detect indirect signs suggesting obstruction and/or inflammation.

conclusionsThe ESUR-SPIWG recommends investigating infertile men with scrotal US focusing on TV, inhomogeneity, localization, varicocele, vas deferens, and epididymal abnormalities. Cryptorchidism, TML, and lesions should be detected in relation to the risk of testicular tumors. CLINICAL RELEVANCE STATEMENT: The ESUR-SPIWG recommendations on scrotal imaging in the assessment of male infertility are useful to standardize the US examination, focus on US abnormalities most associated with abnormal semen parameters in an evidence-based manner, and provide a standardized report to patients. KEY POINTS: So far, ESUR-SPIWG recommendations on scrotal imaging in the assessment of male infertility were not available. The ESUR-SPIWG recommends investigating infertile men with scrotal US focusing on testicular volume, inhomogeneity, localization, varicocele, vas deferens and epididymal abnormalities, and assessing cryptorchidism, testicular microlithiasis and lesions in relation to the risk of testicular tumors. The ESUR-SPIWG recommendations on scrotal imaging in the assessment of male infertility are useful to standardize the US examination, focus on US abnormalities most associated with abnormal sperm parameters in an evidence-based manner, and provide a standardized report to patients.

Indexed as

Infertility, MaleScrotumEuropeHumansMaleSocieties, MedicalUltrasonographyEpididymis and vas deferens ultrasonographyMale infertilityTesticular cancerTesticular ultrasonographyVaricocele

Identifiers

PMID39083089
PMCPMC11782349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.