Evidence map›Paper›PMID 39082780›Full record

ArticleThe Journal of infectious diseases2024

The Impact of Zika Emergence in Remote Communities in Northwestern Ecuador.

Paulina Andrade, Andrea Sosa-Moreno, Sandra Vivero, Victoria Nipaz, Gwenyth O Lee, William Cevallos, Joseph N S Eisenberg, Josefina Coloma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paulina AndradeDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA.
Andrea Sosa-MorenoDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Sandra ViveroCentro de Biomedicina, Universidad Central, Quito, Ecuador.
Victoria NipazInstituto de Microbiología, Colegio de Ciencias Biológicas y Ambientales, Universidad San Francisco de Quito, Quito, Ecuador.
Gwenyth O LeeGlobal Health Institute, Rutgers University, New Brunswick, New Jersey, USA.
William CevallosCentro de Biomedicina, Universidad Central, Quito, Ecuador.
Joseph N S EisenbergDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Josefina ColomaDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA.ORCID 0000-0003-0222-6487

Funding

American Asian Centers for Arbovirus Research and Enhanced Surveillance (A2CARES)U01AI151788 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Josefina Coloma, Eva Harris · 2020 to 2026
$9.6M
Zika and Dengue Co-circulation Under Environmental Change and UrbanizationR01AI132372 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLOMA, JOSEFINA, EISENBERG, JOSEPH N. S. · 2017 to 2020
$2.9M
Arbovirus Transmission Dynamics Across a Metapopulation Undergoing Environmental and Social ChangeR01AI182408 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Josefina Coloma, Joseph N. S. Eisenberg · 2025 to 2026
$1.4M
National Institute of Allergy and Infectious Diseases 1AI132372NIAID NIH HHS R01 AI132372NIAID NIH HHS R01 AI182408NIAID NIH HHS U01 AI151788
6 · The paper itself

Abstract

The Zika virus (ZIKV) epidemic in Latin America (2015-2016) has primarily been studied in urban centers, with less understanding of its impact on smaller rural communities. To address this gap, we analyzed ZIKV seroepidemiology in 6 rural Ecuadorian communities (2018-2019) with varying access to a commercial hub. Seroprevalence ranged from 19% to 54%, measured by nonstructural protein 1 blockade of binding enzyme-linked immunosorbent assay. We observed a decline in ZIKV seroprevalence between 2018 and 2019 that was greater among younger populations, suggesting that the attack rates in the 2015-2016 epidemic were significantly higher than our 2018 observations. These data indicate that the 2015-2016 epidemic included significant transmission in rural and more remote settings. Our observations of high seroprevalence in our area of study highlights the importance of surveillance and research in rural areas lacking robust health systems to manage future Zika outbreaks and vaccine initiatives.

Indexed as

Rural PopulationZika VirusZika Virus InfectionAdolescentAdultAgedAntibodies, ViralChildChild, PreschoolDisease OutbreaksEcuadorFemaleHumansInfantMaleMiddle AgedAntibodies, Viralcommunity cohort studyrural communitiesseroprevalencewaningZika virus

Identifiers

PMID39082780
PMCPMC11566036

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.