Evidence map›Paper›PMID 39082639›Full record

ArticleMultiple sclerosis (Houndmills, Basingstoke, England)2024

The first global landscape analysis of multiple sclerosis research funding.

Bruce Bebo, Tim Coetzee, Emma Gray, Anne Helme, Pamela Kanellis, Douglas Landsman, Michaela Mai, Beatriz Martinez de la Cruz, Julia Morahan, Emmanuelle Plassart and 5 more

Abstract read
In one paragraph

Article in Multiple sclerosis (Houndmills, Basingstoke, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Toward a global research agenda for preventing multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bruce BeboNational Multiple Sclerosis Society, New York, NY, USA.ORCID 0000-0003-0941-9169
Tim CoetzeeNational Multiple Sclerosis Society, New York, NY, USA.ORCID 0000-0002-3031-7549
Emma GrayMultiple Sclerosis Society UK, London, UK.
Anne HelmeMultiple Sclerosis International Federation, London, UK.ORCID 0000-0001-8880-2347
Pamela KanellisMultiple Sclerosis Canada, Toronto, ON, Canada.ORCID 0000-0002-6554-838X
Douglas LandsmanNational Multiple Sclerosis Society, New York, NY, USA.
Michaela MaiGerman Multiple Sclerosis Society, Hannover.ORCID 0000-0001-8959-9096
Beatriz Martinez de la CruzEsclerosis Multiple Espana, Madrid, Spain.
Julia MorahanMultiple Sclerosis Australia, North Sydney, NSW, Australia.
Emmanuelle PlassartFondation ARSEP-French Multiple Sclerosis Research Society, Ivry-sur-Seine, France.
Baylee PickrellMcKing Consulting Corporation, Atlanta, GA, USA.
Sarah RawlingsMultiple Sclerosis Society UK, London, UK.
Lasse SkovgaardDanish Multiple Sclerosis Society, Glostrup, Denmark.
Paola ZaratinItalian Multiple Sclerosis Society, Genoa, Italy.ORCID 0000-0001-8935-4670
Lindsay RechtmanMcKing Consulting Corporation, Atlanta, GA, USA.ORCID 0000-0002-8629-3881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMultiple sclerosis (MS) is an immune-mediated central nervous system disorder and a growing global health challenge affecting nearly 3 million people worldwide. Incidence and prevalence continue to increase with no known cause or cure. Globally governments and non-profit organizations fund research toward better understanding of and treatments for multiple sclerosis.

methodsThis study identified MS research projects funded between 2021 and 2023 by government and non-profit organization sources. Projects were described by type of scientific approach, Pathways to Cure research category (i.e. Stop, Restore, End), and other key characteristics.

resultsOver 2,300 MS research projects were identified through 16 non-profit MS organizations and 18 government databases. The overall global portfolio of these projects is valued at nearly one and a half billion Euros. The majority of projects were classified in the Stop category (60%). Research collaboration occurs in many forms among the research community; around 272 projects were reported to be co-funded.

conclusionGlobal MS research collaboration will accelerate progress toward increased knowledge, effective treatments, improved health outcomes, and ultimately cures for MS. This landscape analysis highlights the current distribution of MS research investment between topics and begins to suggest where the MS community should focus to increase potential impact for current and future endeavors.

Indexed as

Biomedical ResearchMultiple SclerosisGlobal HealthHumansOrganizations, NonprofitResearch Support as Topicfundinglandscape analysisMultiple sclerosis

Identifiers

PMID39082639
PMCPMC11457431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.