Evidence map›Paper›PMID 39082085›Full record

ArticleThe science of diabetes self-management and care2024

Medication Engagement, Determinants of Health, and A1C Levels Among Adults With Type 2 Diabetes within a Tribal Health System.

Tarah Nelson, Diana J Wilkie, Yingwei Yao, Richard Segal, Ashley DeVaughan-Circles, William T Donahoo, R Turner Goins, Spero M Manson, Anatolia B Legaspi, Lisa Scarton

Abstract read
In one paragraph

Article in The science of diabetes self-management and care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tarah NelsonUniversity of Florida, College of Nursing, Gainesville, Florida.ORCID 0000-0003-3080-8847
Diana J WilkieUniversity of Florida, College of Nursing, Gainesville, Florida.
Yingwei YaoUniversity of Florida, College of Nursing, Gainesville, Florida.
Richard SegalUniversity of Florida, College of Pharmacy, Gainesville, Florida.
Ashley DeVaughan-CirclesChoctaw Nation of Oklahoma, Choctaw Nation Health Services Authority, Talihina, Oklahoma.
William T DonahooUniversity of Florida, College of Medicine, Gainesville, Florida.
R Turner GoinsWestern Carolina University, College of Health and Human Sciences, Cullowhee, North Carolina.
Spero M MansonUniversity of Colorado Anschutz Medical Campus, Centers for American Indian and Alaska Native Health, Aurora, Colorado.
Anatolia B LegaspiUniversity of Florida, College of Pharmacy, Gainesville, Florida.
Lisa ScartonUniversity of Florida, College of Nursing, Gainesville, Florida.

Funding

Medication Adherence and Cardio-Metabolic Control Indicators among Adult American Indians Receiving Tribal Health ServicesR01NR020386 · NINR · UNIVERSITY OF FLORIDA · PI SCARTON, LISA · 2022 to 2025
$2.0M
NINR NIH HHS R01 NR020386
6 · The paper itself

Abstract

purposeThe purpose of this study was to examine the association between determinants of health, medication engagement, and A1C levels in adults with type 2 diabetes (T2DM) receiving Tribal health and pharmacy services.

methodsA retrospective analysis of 2020-2021 electronic health record data was conducted and included adult patients with T2DM using Choctaw Nation Health Services Authority prescribed ≥1 noninsulin glucose-lowering medication in 2020, had ≥1 A1C value in 2020 and 2021, and had a valid zip code in 2021. Patients receiving both insulin and other noninsulin glucose-lowering medication were included. The proportion of days covered (PDC) was used to calculate medication engagement. Statistical analyses included bivariate analysis and linear regression.

resultsThere were 3787 patients included in the analyses; 62.5% were considered engaged (PDC ≥ 0.8). The mean 2020 A1C level was 8.0 (64 mmol/mol) ± 1.8; 33% had an A1C of <7%, 42% had an A1C of 7% to 9%, and 25% had an A1C >9%. The mean A1C in 2021 was 7.9 (63 mmol/mol) ± 1.7; 34% had an A1C of <7%, 44% had an A1C of 7% to 9%, and 22% had an A1C >9%. Older age was weakly correlated with higher engagement; higher engagement was associated with lower A1C levels while adjusting for covariates.

conclusionsMedication engagement was associated with lower A1C levels, and older age was weakly associated with higher engagement to noninsulin glucose-lowering medications, consistent with previous literature. No determinants of health were significantly associated with A1C levels while adjusting for covariates.

Indexed as

Diabetes Mellitus, Type 2Glycated HemoglobinHypoglycemic AgentsAdultAgedDrug MonitoringFemaleHumansMaleMiddle AgedRetrospective StudiesGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic Agents

Identifiers

PMID39082085
PMCPMC11580797

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.