Evidence map›Paper›PMID 39082046›Full record

ArticleCureus2024

Through Different Lenses: A Retrospective Analysis of the Agreement Between Laparoscopic and Histopathological Evaluations of the Appendix.

Christine-Bianca Hanganu, Sanad Isswiasi, Abiodun Adigun, Kyrllos Farag, Vladimir Nichita, Muhammadhasan Anwaar, Ahmed Esawi, Rishi Sen, Akshay Bavikatte, Elisabeth Drye

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Postoperative abdominal wall actinomycosis mimicking malignancy: a case report and literature review.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christine-Bianca HanganuGeneral Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.
Sanad IsswiasiGeneral Surgery, West Suffolk Hospital, Bury St Edmunds, GBR.
Abiodun AdigunCardiothoracic Surgery, Manchester University NHS Foundation Trust, Manchester, GBR.
Kyrllos FaragGeneral Surgery and Oncoplastic Breast Surgery, West Suffolk Hospital, Bury St Edmunds, GBR.
Vladimir NichitaGeneral Surgery, Peterborough City Hospital, Peterborough, GBR.
Muhammadhasan AnwaarGeneral Surgery, West Suffolk Hospital, Bury St Edmunds, GBR.
Ahmed EsawiGeneral Surgery, West Suffolk Hospital, Bury St Edmunds, GBR.
Rishi SenGeneral Surgery, West Suffolk Hospital, Bury St Edmunds, GBR.
Akshay BavikatteColorectal Surgery, West Suffolk Hospital, Bury St Edmunds, GBR.
Elisabeth DryeGeneral Surgery, Peterborough City Hospital, Peterborough, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAppendicectomy is the most frequently performed emergency general surgical procedure. Previous research has highlighted discrepancies between initial intraoperative laparoscopic diagnoses and subsequent histopathology reports following appendicectomy. In the United Kingdom (UK), routine histopathological examination is the established practice, ensuring precise diagnosis of appendiceal specimens. This retrospective analysis aims to compare intraoperative laparoscopic assessments of the appendix with corresponding histopathology findings. METHODOLOGY: We conducted a retrospective analysis of 418 consecutive emergency laparoscopic appendectomies at Peterborough City Hospital in the UK between April 2018 and June 2019 for suspected appendicitis. Intraoperative findings were compared with histopathological examination outcomes using kappa statistics.

resultsOf the 418 appendectomies analysed, we found a substantial agreement between surgeons and pathologists (kappa = 0.71, P < 0.001) in detecting overall abnormalities of appendices. This agreement was also high for detecting inflamed appendices (kappa = 0.72, P < 0.001). However, of the six neoplastic lesions confirmed in the pathologists' final report, only two were suspected during laparoscopy.

conclusionsWhile laparoscopic assessments of the appendix demonstrate a statistically significant and improved agreement with histopathological findings in detecting abnormal and inflamed appendices, the ability of surgeons to identify neoplasia appears suboptimal based on our small sample of neoplasia cases. The data strongly support the continued practice of routine histopathological examination following appendicectomy due to its crucial role in avoiding missed diagnoses and ensuring better patient outcomes.

Indexed as

appendicectomyappendicitishistopathology reportlaparoscopic assessmentlaparoscopic diagnosispost-operative histopathologyvermiform appendix

Identifiers

PMID39082046
PMCPMC11288700

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.