Evidence map›Paper›PMID 39081971›Full record

ArticleFrontiers in dementia2023

Organ donation after euthanasia in a patient living with dementia: a landmark case report.

Nathalie van Dijk, Fabiënne Vliegen, Angelique Ham, Wim de Jongh, Freek Jan Berkhout, Jeroen Blankevoort, Rankie Ten Hoopen, Jan Bollen, Walther van Mook

Abstract readCase Reports
In one paragraph

Article in Frontiers in dementia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Organ donation after euthanasia starting at home: a mixed-methods study of preliminary nationwide Dutch experiences.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nathalie van Dijk *Department of Intensive Care Medicine, Maastricht University Medical Center+, Maastricht, Netherlands.
Fabiënne Vliegen *Faculty of Law, Maastricht University, Maastricht, Netherlands.
Angelique HamDepartment of Organ Donation Coordination, Amsterdam University Medical Center, Amsterdam, Netherlands.
Wim de JonghDepartment of Organ Donation Coordination, Maastricht University Medical Center+, Maastricht, Netherlands.
Freek Jan BerkhoutExpertisecentrum Euthanasie (EE), The Hague, Netherlands.
Jeroen BlankevoortDepartment of Neurology, Flevo Hospital, Almere, Netherlands.
Rankie Ten HoopenFaculty of Law, Maastricht University, Maastricht, Netherlands.
Jan BollenDepartment of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Walther van MookDepartment of Intensive Care Medicine, Maastricht University Medical Center+ and School of Health Professions Education, Maastricht University, Maastricht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Organ donation after euthanasia (ODE) has been performed over 100 times in the Netherlands, primarily involving patients suffering from a neurodegenerative or psychiatric disease. In recent years, the number of euthanasia cases related to dementia has increased in the Netherlands, with some patients living with dementia expressing a wish for organ donation after euthanasia. Methods: We describe a unique case of a 67-year-old female diagnosed with primary progressive aphasia as part of frontotemporal dementia who requested and underwent organ donation after euthanasia. Results: The patient had expressed her explicit wishes for both euthanasia and organ donation, which were discussed with her family physician, the Euthanasia Expertise Center (EE), and an organ donation coordinator. The patient was informed that to proceed with ODE, she should still be capable of voicing a voluntary and well-considered request for organ donation. The legally required euthanasia assessment procedure was carefully completed before ODE. Multiple healthcare professionals assessed the patient's competence, voluntariness, and unbearable suffering. Thereafter the patient's ODE request was granted, and both lungs and kidneys were successfully donated and transplanted. Conclusions: This unique case demonstrates that ODE is feasible from medical, ethical, and legal perspectives in patients living with dementia. This case highlights several aspects essential to enable an ODE request by a patient living with dementia to be granted, such as the role of the physician performing euthanasia, the relevance of the decision-making capacity of the patient, the presence of an advance directive, and the involvement of and support by relatives and caregivers. However, several unresolved ethical issues surrounding ODE in patients with dementia, especially in patients with advanced stages of dementia, warrant further exploration, including the timing of discussing organ donation after the initial euthanasia request.

Indexed as

advance careadvance directivecasedementiaeuthanasialegislationorgan donation

Identifiers

PMID39081971
PMCPMC11285699

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.