Evidence map›Paper›PMID 39081964›Full record

ArticleOncology letters2024

Occupational radiation exposure and risk of thyroid cancer: A meta‑analysis of cohort studies.

Huiling Qu, Chao He, Haichun Xu, Xue Ren, Xiaoyu Sun, Ying Xu

Abstract read
In one paragraph

Article in Oncology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huiling QuDepartment of Neurology, The General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China.
Chao HeDepartment of Neurology, The General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China.
Haichun XuDepartment of Psychiatry, Shenyang Jing'an Mental Health Hospital, Shenyang, Liaoning 110000, P.R. China.
Xue RenDepartment of Tumor Radiotherapy, The General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China.
Xiaoyu SunDepartment of Neurology, The General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China.
Ying XuDepartment of Tumor Radiotherapy, The General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between occupational exposure to ionizing radiation and the risk of thyroid cancer remains unclear in medical research. The present meta-analysis assessed whether occupational radiation exposure increases the risk of thyroid cancer. The PubMed, China National Knowledge Infrastructure, Embase, ChinaInfo, Weipu and Chinese Biomedical Literature databases were comprehensively searched for cohort studies published up to January 1st, 2023, using medical subject headings and keywords. Subsequently, a meta-analysis was conducted to determine a pooled-effect estimate of the association between occupational exposure and thyroid cancer. Subgroup analyses by sex were performed. The results were presented as the overall odds ratio (OR) and 95% confidence interval (CI). A total of six studies (covering 3,409,717 individuals), which were published between 2006 and 2021 from 4 countries met the inclusion criteria. The number of participants per study ranged from 67,562 to 2,992,166 and the number of cancer events in each study ranged from 134 to 2,599 cases. Pooled analyses indicated that occupational radiation exposure was associated with a 67% higher risk of thyroid cancer (OR=1.61, 95% CI: 1.27-2.04, P<0.001). Male patients with a history of occupational radiation exposure exhibited a slightly higher risk of thyroid cancer than female patients (OR=1.74, 95% CI: 1.61-1.87, P=0.726 vs. OR=1.30, 95% CI: 1.15-1.48, P=0.032). Collectively, the data indicated that occupational exposure to ionizing radiation was associated with the risk of thyroid cancer. However, further studies are warranted to confirm these preliminary findings.

Indexed as

cohort studyionizing radiationoccupational exposurethyroid cancer

Identifiers

PMID39081964
PMCPMC11287109

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.