Evidence map›Paper›PMID 39081846›Full record

ArticleAdvances in radiation oncology2024

Improving the Efficiency of Single-Isocenter Multiple Metastases Stereotactic Radiosurgery Treatment.

Jonathan J Wyatt, Rekha Mohanraj, Judith H Mott

Abstract read
In one paragraph

Article in Advances in radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan J WyattNorthern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom.
Rekha MohanrajNorthern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom.
Judith H MottNorthern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Multiple brain metastases can be treated efficiently with stereotactic radiosurgery (SRS) using a single-isocenter dynamic conformal arc (SIDCA) technique. Currently, plans are manually optimized, which may lead to unnecessary table angles and arcs being used. This study aimed to evaluate an automatic 4π optimization SIDCA algorithm for treatment efficiency and plan quality. Methods and Materials: Automatic 4π-optimized SIDCA plans were created and compared with the manually optimized clinical plans for 54 patients who underwent single-fraction SRS for 2 to 10 metastases. The number of table angles and number of arcs were compared with a paired Results: The automatic plans significantly improved treatment efficiency with a mean reduction in the number of table angles and arcs of -0.5 ± 0.1 and -1.3 ± 0.2, respectively (±SE; both Conclusions: Automatic 4π optimization can generate SIDCA SRS plans with improved treatment efficiency and noninferior plan quality.

Identifiers

PMID39081846
PMCPMC11286980

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.