Evidence map›Paper›PMID 39081786›Full record

ArticlePNAS nexus2024

Engineered skin microbiome reduces mosquito attraction to mice.

Feng Liu, Iliano V Coutinho-Abreu, Robyn Raban, Tam Thuy Dan Nguyen, Alejandra R Dimas, Joseph A Merriman, Omar S Akbari

Abstract read
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Feng LiuDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.ORCID https://orcid.org/0000-0003-3517-9824
Iliano V Coutinho-AbreuDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.ORCID https://orcid.org/0000-0002-1389-1071
Robyn RabanDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.ORCID https://orcid.org/0000-0002-5648-6770
Tam Thuy Dan NguyenSarafan ChEM-H, Stanford University, 290 Jane Stanford Way, Stanford, CA 94305, USA.
Alejandra R DimasSarafan ChEM-H, Stanford University, 290 Jane Stanford Way, Stanford, CA 94305, USA.
Joseph A MerrimanSarafan ChEM-H, Stanford University, 290 Jane Stanford Way, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0002-0725-2265
Omar S AkbariDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.ORCID https://orcid.org/0000-0002-6853-9884

Funding

Olfactory modulation of color vision and behavior in mosquitoesR01AI175152 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Jeffrey A Riffell · 2023 to 2026
$3.2M
NIAID NIH HHS R01 AI175152
6 · The paper itself

Abstract

The skin microbiome plays a pivotal role in the production of attractive cues detected by mosquitoes. Here, we leveraged recent advances in genetic engineering to significantly reduce the production of L-(+)-lactic acid as a strategy to reduce mosquito attraction to the highly prominent skin commensals

Indexed as

Corynebacterium amycolatumengineered human skin microbiotalactic acidmosquito repellencyStaphylococcus epidermidis

Identifiers

PMID39081786
PMCPMC11287867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.