ArticleBio-algorithms and med-systems2023
Application of quantum entanglement induced polarization for dual-positron and prompt gamma imaging.
Article in Bio-algorithms and med-systems, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Nonmaximal entanglement of photons from positron-electron annihilation demonstrated using a plastic PET scanner.Science advances · 2025Article
- Quantum Entanglement Filtering: A PET feasibility study in imaging dual-positron and prompt gamma emission via Monte Carlo simulation.IEEE transactions on radiation and plasma medical sciences · 2024Article
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3 authors.
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Abstract
The intrinsic resolution of Positron Emission Tomography (PET) imaging is bound by positron range effects, wherein the radioactive decay of the imaging tracer occurs at a disjoint location from positron annihilation. Compounding this issue are the variable ranges positrons achieve, depending on tracer species (the energy they are emitted with) and the medium they travel in (bone vs soft tissue, for example) - causing the range to span more than an order of magnitude across various study scenarios (~0.19 mm to ~6.4 mm). Radioisotopes, such as Zr-89, exhibit dual emissions of positron and prompt gammas, offering an opportunity for accurate tracer positioning as prompt gammas originate from the tracer location. These multi-emission radiotracers have historically suffered from increased noise corresponding to the third gamma interfering in annihilation gamma coincidence pairing. Recent advancements, however, have brought to light the unique property of annihilation gammas having scattering kinematics distinct from random gamma pairs. These properties are born from the singular quantum entanglement state available to the gamma pair following para-positronium decay which prescribes linearly orthogonal polarization. Such coherent polarization is not shared by prompt gamma emissions, offering an opportunity for their discrimination. We present an investigation into this technique, comparing the distribution of relevant scattering kinematics of entangled annihilation gammas and corresponding prompt gammas via a Monte Carlo simulation.
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