ArticleJuntendo Iji zasshi = Juntendo medical journal2022
Historical Changes in Anesthesia Practice for Laparoscopic Gynecological Surgery at Juntendo University Hospital - A Retrospective Observational Study Focusing on Factors Affecting the Incidence of Postoperative Nausea and Vomiting.
Article in Juntendo Iji zasshi = Juntendo medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Previously, we reported that antiemetics (droperidol and/or dexamethasone) could significantly reduce the incidence of postoperative nausea and vomiting (PONV) after laparoscopic gynecological surgery (LGS). We retrospectively investigated anesthesia practice during the era earlier than the above-mentioned report to identify factors affecting PONV. Methods: We investigated 1,221 patients who underwent LGS at Juntendo University Hospital between 2007 and 2009. Effects of nine covariates likely to affect PONV on the actual incidence of PONV were examined with the multivariate logistic regression analysis. Results: The actual incidence of PONV developing until nine hours after the transfer to the ward was 47.3% (577/1,221) in the total cohort. The multivariate logistic regression analysis revealed that longer duration of anesthesia (in hours) was associated with the increased incidence of PONV (odds ratio [OR], 1.170; 95% confidence interval [CI], 1.000-1.360; Conclusions: Longer duration of anesthesia was associated with the increased incidence of PONV. Addition of droperidol to the PCA infusate and the use of reversal agent neostigmine co-administrated with atropine were associated with the reduced incidence of PONV.
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