Evidence map›Paper›PMID 39081344›Full record

ArticleFrontiers in neurology2024

Ischemic perfusion radiomics: assessing neurological impairment in acute ischemic stroke.

Jiaxi Lu, Mazen M Yassin, Yingwei Guo, Yingjian Yang, Fengqiu Cao, Jiajing Fang, Asim Zaman, Haseeb Hassan, Xueqiang Zeng, Xiaoqiang Miao and 6 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jiaxi LuSchool of Applied Technology, Shenzhen University, Shenzhen, China.
Mazen M YassinCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen, China.
Yingwei GuoSchool of Electrical and Information Engineering, Northeast Petroleum University, Daqing, China.
Yingjian YangDepartment of Radiological Research and Development, Shenzhen Lanmage Medical Technology Co., Ltd., Shenzhen, China.
Fengqiu CaoSchool of Information Science and Engineering, Shenyang Polytechnic University, Shenyang, China.
Jiajing FangShenzhen Academy of Metrology and Quality Inspection, Shenzhen, China.
Asim ZamanCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen, China.
Haseeb HassanCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen, China.
Xueqiang ZengSchool of Applied Technology, Shenzhen University, Shenzhen, China.
Xiaoqiang MiaoCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen, China.
Huihui YangSchool of Applied Technology, Shenzhen University, Shenzhen, China.
Anbo CaoSchool of Applied Technology, Shenzhen University, Shenzhen, China.
Guangtao HuangSchool of Applied Technology, Shenzhen University, Shenzhen, China.
Taiyu HanSchool of Applied Technology, Shenzhen University, Shenzhen, China.
Yu LuoDepartment of Radiology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Yan KangSchool of Applied Technology, Shenzhen University, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Accurate neurological impairment assessment is crucial for the clinical treatment and prognosis of patients with acute ischemic stroke (AIS). However, the original perfusion parameters lack the deep information for characterizing neurological impairment, leading to difficulty in accurate assessment. Given the advantages of radiomics technology in feature representation, this technology should provide more information for characterizing neurological impairment. Therefore, with its rigorous methodology, this study offers practical implications for clinical diagnosis by exploring the role of ischemic perfusion radiomics features in assessing the degree of neurological impairment. Methods: This study employs a meticulous methodology, starting with generating perfusion parameter maps through Dynamic Susceptibility Contrast-Perfusion Weighted Imaging (DSC-PWI) and determining ischemic regions based on these maps and a set threshold. Radiomics features are then extracted from the ischemic regions, and the Results: The results show that the proposed method outperforms the original perfusion parameters, radiomics features of the infarct and hypoxic regions, and their combinations, achieving an accuracy of 0.926, sensitivity of 0.923, specificity of 0.929, PPV of 0.923, NPV of 0.929, and AUC of 0.923, respectively. Conclusion: The proposed method effectively assesses the degree of neurological impairment in AIS patients, providing an objective auxiliary assessment tool for clinical diagnosis.

Indexed as

acute ischemic strokeDSC-PWIneurological impairmentperfusion parametersradiomics

Identifiers

PMID39081344
PMCPMC11286473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.