Evidence map›Paper›PMID 39081315›Full record

ArticleFrontiers in immunology2024

A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus.

Tony W Ng, Wakako Furuyama, Ariel S Wirchnianski, Noemí A Saavedra-Ávila, Christopher T Johndrow, Kartik Chandran, William R Jacobs, Andrea Marzi, Steven A Porcelli

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Tony W NgDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Wakako FuruyamaLaboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Hamilton, MT, United States.
Ariel S WirchnianskiDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Noemí A Saavedra-ÁvilaDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Christopher T JohndrowDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Kartik ChandranDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Andrea MarziLaboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Hamilton, MT, United States.
Steven A PorcelliDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI Ulrich Steidl · 1985 to 2026
$111.2M
Immunobiology, molecular virology and countermeasures of highly pathogenic virusesZIAAI001254 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARZI, ANDREA · 2020 to 2025
$16.6M
Cytek Aurora Multiparameter Flow CytometerS10OD026833 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PORCELLI, STEVEN A · 2019 to 2019
$367k
High-speed/resolution whole slide scanner supported by two core facilitiesS10OD019961 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S · 2015 to 2015
$326k
NCI NIH HHS P30 CA013330NIH HHS S10 OD019961NIH HHS S10 OD026833
6 · The paper itself

Abstract

Previous studies have demonstrated the efficacy and feasibility of an anti-viral vaccine strategy that takes advantage of pre-existing CD4

Indexed as

Antibodies, ViralBCG VaccineEbola VaccinesEbolavirusHemorrhagic Fever, EbolaAnimalsDisease Models, AnimalFemaleHumansImmunizationImmunoglobulin Class SwitchingMiceMice, Inbred C57BLReceptors, IgGT-Lymphocytes, Helper-InducerVaccinationAntibodies, ViralBCG VaccineEbola VaccinesReceptors, IgGantibodiesCD4+ T cellsEbola virusFc receptorsintrastructural helpMycobacterium bovis BCGvaccines

Identifiers

PMID39081315
PMCPMC11286471

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.