Evidence map›Paper›PMID 39081301›Full record

ArticleACG case reports journal2024

Gastric Signet Ring Cell Adenocarcinoma With Metastasis to the Testicles and Leptomeninges.

Hamzah Shariff, Tristan Luu, Haluk Kavis, Joshua Obuch

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hamzah ShariffGeisinger Commonwealth School of Medicine, Scranton, PA.ORCID https://orcid.org/0000-0002-1773-0144
Tristan LuuDepartment of Internal Medicine, Geisinger Wyoming Valley Medical Center, Wilkes Barre, PA.
Haluk KavisDepartment of Clinical and Laboratory Pathology, Geisinger Medical Center, Danville, PA.
Joshua ObuchDepartment of Gastroenterology, Geisinger Wyoming Valley Medical Center, Wilkes Barre, PA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric signet ring cell adenocarcinoma (SRCA) is an aggressive malignancy primarily diagnosed in advanced stages. Metastasis to other organ systems is uncommon, however, associated with poor prognosis. We present a young patient with persistent pain in the testicle. Histopathologic examination of the resected testicle revealed metastatic signet ring adenocarcinoma prompting follow-up endoscopy with biopsy confirming gastric SRCA. After 10 months of systemic chemotherapy, the patient developed worsening headaches, and cerebrospinal fluid cytology confirmed leptomeningeal metastasis. This case underscores the rare manifestation of SRCA and the importance of vigilance for atypical presentations to ensure timely diagnosis and management.

Indexed as

adenocarcinomaleptomeningesmetastasisringsignettesticle

Identifiers

PMID39081301
PMCPMC11286243

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.