Evidence map›Paper›PMID 39081110›Full record

ArticleBritish journal of pharmacology2024

Blockade of Ca

Osbaldo Lopez-Charcas, Oumnia Benouna, Roxane Lemoine, Margarita Jacaranda Rosendo-Pineda, Tonantzin Guadalupe Anguheven-Ledezma, Lizeth Sandoval-Vazquez, Martin Leonardo Gallegos-Gomez, Leticia Robles-Martinez, Zazil Herrera-Carrillo, Miguel Ramírez-Aragón and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. The Functional Interplay among GAD2, GABRG2, and CACNA1G Genes in Cancers.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  4. Calcium channels as pharmacological targets for cancer therapy.Clinical and experimental medicine · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Osbaldo Lopez-CharcasDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-5080-8310
Oumnia BenounaUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.
Roxane LemoineUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.
Margarita Jacaranda Rosendo-PinedaDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Tonantzin Guadalupe Anguheven-LedezmaDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID https://orcid.org/0009-0005-8029-6167
Lizeth Sandoval-VazquezDepartment of Biochemistry, CINVESTAV, Mexico City, Mexico.
Martin Leonardo Gallegos-GomezDepartment of Biochemistry, CINVESTAV, Mexico City, Mexico.
Leticia Robles-MartinezDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Zazil Herrera-CarrilloDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Miguel Ramírez-AragónDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Ana AlfaroServicio de Anatomía Patológica, Hospital General de México 'Dr. Eduardo Liceaga', Mexico City, Mexico.
Stéphanie ChadetUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.
Fabio FerroUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.ORCID https://orcid.org/0000-0002-2982-0024
Pierre BessonUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.
Lin-Hua JiangUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.
Sadanandan E VeluDepartment of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Agustín Guerrero-HernandezDepartment of Biochemistry, CINVESTAV, Mexico City, Mexico.
Sébastien RogerUniversité de Tours, Inserm U1327 ISCHEMIA 'Membrane Signalling and Inflammation in Reperfusion Injuries', Tours, France.
Juan Carlos GomoraDepartamento de Neuropatología Molecular, División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.

Funding

Somatostatin receptor 2 (SSTR2) antibody-drug conjugate for pancreatic neuroendocrine tumor (PanNET) therapyR21CA226491 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JASKULA-SZTUL, RENATA, LIU, XIAOGUANG MARGARET · 2020 to 2021
$364k
Biotechnology and Biological Sciences Research Council, UK BB/C517317/1Conseil Régional du Centre-Val de Loire, France CanalExConseil Régional du Centre-Val de Loire, France NavMetargetConsejo Nacional de Ciencia y Tecnologia (CONACYT), Mexico A1-S-19171Consejo Nacional de Ciencia y Tecnologia (CONACYT), Mexico CVU1148606Consejo Nacional de Ciencia y Tecnologia (CONACYT), Mexico I1200/320/2022 CVU 369878Department of Education of the Henan Province, China 16IRTSTHN020Disciplinary Group of Psychology and Neuroscience, Xinxiang Medical University, China 2016PN-KFKT-06Fondation pour la Recherche Médicale (FRM), France SPF201909009198Le Cancer du sein, parlons-en, France PrixRubanRoseAvenirLigue Nationale Contre le Cancer, Interrégion Grand-Ouest: comités 29, 36, 86 and 37, FranceMinistère de la Recherche et des Technologies, FranceNational High-End Foreign Expert Recruitment Plan of China, China G2022026006LNational Institutes of Health (NIH), USA 1R21CA226491NCI NIH HHS R21 CA226491O'Neal Comprehensive Cancer Center, USA pre-R01grantPAPIIT-DGAPA-UNAM, Mexico IN209820Université de Tours, FranceWellcome TrustWellcome Trust, UK 099758/Z/12/Z
6 · The paper itself

Abstract

background and purposeGastrointestinal tumours overexpress voltage-gated calcium (Ca EXPERIMENTAL APPROACH: Transcripts for Ca KEY

resultsHigh levels of Ca CONCLUSION AND IMPLICATIONS: Gossypol differentially blocked Ca

Indexed as

Calcium Channel BlockersCalcium Channels, T-TypeCell ProliferationColonic NeoplasmsGossypolAntineoplastic AgentsCalciumCell Line, TumorG1 Phase Cell Cycle CheckpointsHumansResting Phase, Cell CycleAntineoplastic AgentsCalciumCalcium Channel BlockersCalcium Channels, T-TypeGossypolblocking mechanismCaV3 calcium channelsgastrointestinal cancersgossypolion channel blockersTTA‐P2

Identifiers

PMID39081110
PMCPMC11613961

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.