Evidence map›Paper›PMID 39080634›Full record

Trial reportBMC women's health2024

Effect of dairy products fortified with vitamin d

Payam Sharifan, Toktam Sahranavard, Mohammad Rashidmayvan, Susan Darroudi, Mohammad Vahedi Fard, Kimia Mohammadhasani, Amin Mansoori, Saeid Eslami, Mohamad Safarian, Asma Afshari and 7 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC women's health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Payam Sharifan *Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Toktam Sahranavard *Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Rashidmayvan *Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Susan DarroudiVascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Vahedi FardDepartment of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran.
Kimia MohammadhasaniDepartment of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran.
Amin MansooriDepartment of Applied Mathematics, School of Mathematical Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
Saeid EslamiDepartment of Medical Informatics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohamad SafarianDepartment of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Asma AfshariDepartment of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad BagherniyaDepartment of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Maryam TayefiNorwegian Center for e-health Research, University Hospital of North Norway, Tromsø, Norway.
Majid Khadem-RezaiyanClinical Research Development Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Hamideh GhazizadehStudent Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon FernsBrighton and Sussex Medical School, Division of Medical Education, Brighton, UK.
Mitra RezaieDepartment of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. rezaeim1@mums.ac.ir.
Majid Ghayour-MobarhanDepartment of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. ghayourmobarhan@yahoo.com.

Funding

National Institute for Medical Research Development IR.NIMAD.REC.1396.027
6 · The paper itself

Abstract

backgroundsRestless legs syndrome (RLS) is an unpleasant condition that affects the quality of life of patients. Its prevalence in increased in women with premenstrual syndrome (PMS). Vitamin D plays a key role in female reproduction through its impact on calcium homeostasis and neurotransmitters. We aimed to evaluate the effect of dairy products fortified with Vitamin D MATERIALS AND

methodsWe conducted a 2.5-month, randomized, total-blinded clinical trial to evaluate the effectiveness of low-fat milk and yogurt fortified with vitamin D on RLS in women with PMS. Among 141 middle-aged women with abdominal obesity, 71 and 70 cases received fortified and non-fortified low-fat dairy products, respectively. All subjects completed a Symptoms Screening Tool (PSST) and RLS questionnaires.

resultsThe results showed that in the women with severe PMS (PSST > 28), serum levels of vitamin D increased significantly following vitamin D fortification. The mean restless legs score in the severe PMS subgroup (PSST > 28) was significantly lower after the intervention (p < 0.05. Serum Vitamin D levels significantly differed between intervention and control groups in all individuals (PSST < 19, PSST 19-28, and PSST > 28) (p < 0.05), but no significant differences were found between RLS scores of the intervention and control groups in the three PMS subgroups (p > 0.05).

conclusionFortifying dairy products with vitamin D

Indexed as

CholecalciferolDairy ProductsFood, FortifiedObesity, AbdominalPremenstrual SyndromeRestless Legs SyndromeVitamin D DeficiencyAdultFemaleHumansMiddle AgedPilot ProjectsCholecalciferolFortificationLow-fat dairyPremenstrual syndromeRestless legs syndromeVitamin D

Identifiers

PMID39080634
PMCPMC11287967

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.