Evidence map›Paper›PMID 39080504›Full record

ArticleLab animal2024

Refined tamoxifen administration in mice by encouraging voluntary consumption of palatable formulations.

Dominique Vanhecke, Viola Bugada, Regula Steiner, Bojan Polić, Thorsten Buch

Abstract read
In one paragraph

Article in Lab animal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chewable Tablets for Precise Unit Dosing of Animals.Journal of pharmaceutical innovation · 2026
    Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dominique VanheckeInstitute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-7625-1071
Viola BugadaInstitute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland.
Regula SteinerInstitute of Clinical Chemistry, University and University Hospital of Zurich, Zurich, Switzerland.ORCID 0009-0001-1617-6524
Bojan PolićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Thorsten BuchInstitute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland. Thorsten.Buch@uzh.ch.ORCID 0000-0002-2236-9074

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) BU1410/1-2Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 310030_116201Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 310030_132713 / 1
6 · The paper itself

Abstract

Drug administration in preclinical rodent models is essential for research and the development of novel therapies. Compassionate administration methods have been developed, but these are mostly incompatible with water-insoluble drugs such as tamoxifen or do not allow for precise timing or dosing of the drugs. For more than two decades, tamoxifen has been administered by oral gavage or injection to CreER

Indexed as

TamoxifenAnimalsFemaleMaleMiceMice, Inbred C57BLTamoxifen

Identifiers

PMID39080504
PMCPMC11291282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.