Evidence map›Paper›PMID 39080403›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

The impact of a multidisciplinary intervention to reduce severe retinopathy of prematurity in Kampala, Uganda.

Victoria Nakibuuka, Yvonne E Vaucher, Lucy Namakula, Sarah Kasozi, Jason Zhang, Anna L Ells, Mike P Blair, Sherwin J Isenberg, Scott R Lambert, Sarah H Rodriguez

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Victoria NakibuukaSt. Francis Hospital Nsambya, Kampala, P.O. Box 7146, Uganda.
Yvonne E VaucherDivision of Neonatology, Department of Pediatrics, University of California San Diego, San Diego, CA, 92037-7774, USA.
Lucy NamakulaSt. Francis Hospital Nsambya, Kampala, P.O. Box 7146, Uganda.
Sarah KasoziSt. Francis Hospital Nsambya, Kampala, P.O. Box 7146, Uganda.
Jason ZhangDepartment of Ophthalmology and Visual Science, The University of Chicago, Chicago, IL, USA.
Anna L EllsCalgary Retina Consultants, Department of Surgery, University of Calgary, Calgary, AB, T2H 0C8, Canada.
Mike P BlairDepartment of Ophthalmology and Visual Science, The University of Chicago, Chicago, IL, USA.
Sherwin J IsenbergJules Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Scott R LambertDepartment of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, 94303, USA.
Sarah H RodriguezDepartment of Ophthalmology and Visual Science, The University of Chicago, Chicago, IL, USA. srodriguez5@bsd.uchicago.edu.ORCID 0000-0001-7919-0852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo address the threat of retinopathy of prematurity (ROP) in Sub-Saharan Africa (SSA), the Stop Infant Blindness in Africa (SIBA) project introduced a comprehensive program, including subspecialty training and oxygen management equipment.

methodsA before-and-after retrospective cohort study compared preterm infants < 1750 g or < 34 weeks' gestation before (2022) and after (2023) program implementation. Outcomes included: the proportion with severe ROP, the proportion with Zone III vascularization on first examination, and factors associated with severe ROP.

resultsOverall, 140 infants were screened before and 122 after program implementation. The proportion with Zone III vascularization increased from 16.1% (N = 11) pre-intervention to 44.9% (N = 32) post-intervention (p = 0.001). The proportion with severe ROP decreased from 27.8% (N = 19) to 12.8% (N = 9, p = 0.03). Factors predicting severe ROP on adjusted analyses were gestational age and blood transfusion.

conclusionIn SSA, introduction of a comprehensive program to prevent and treat ROP can decrease the risk of severe ROP.

Indexed as

Retinopathy of PrematurityFemaleGestational AgeHumansInfant, NewbornInfant, PrematureMaleRetrospective StudiesRisk FactorsSeverity of Illness IndexUganda

Identifiers

PMID39080403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.