ArticleIntensive care medicine experimental2024
Mechanical power ratio threshold for ventilator-induced lung injury.
Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Power, Duration, and Compliance: Reframing Risk of Ventilatory-Induced Lung Injury With the Risk-Adjusted Mechanical-Power Score.Critical care medicine · 2026Article
- Redefining mechanical ventilation in thoracic anesthesia: flow-controlled ventilation from bench to bedside-a narrative review.Frontiers in medicine · 2026Review
- Revisiting ventilator-induced lung injury: from mechanical power to immunometabolic interaction.Frontiers in immunology · 2026Review
- Mechanical power normalisation methods to predict ICU mortality: a retrospective cohort study.Annals of intensive care · 2025Article
- Article
- Predictors of VILI risk: driving pressure, 4DPRR and mechanical power ratio-an experimental study.Intensive care medicine experimental · 2024Article
- How to minimize mechanical power during controlled mechanical ventilation.Intensive care medicine experimental · 2024Article
- Bedside Assessment of the Respiratory System During Invasive Mechanical Ventilation.Journal of clinical medicine · 2024Review
- Correction: Mechanical power ratio threshold for ventilator-induced lung injury.Intensive care medicine experimental · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleMechanical power (MP) is a summary variable incorporating all causes of ventilator-induced-lung-injury (VILI). We expressed MP as the ratio between observed and normal expected values (MP
objectiveTo define a threshold value of MP
methodsIn a population of 82 healthy pigs, a threshold of MP MEASUREMENTS AND MAIN
resultsWe measured physiological variables every six hours. At the end of the experiment, we measured lung weight and wet-to-dry ratio to quantify edema. Histological samples were analyzed for alveolar ruptures, inflammation, alveolar edema, atelectasis. An MP LIMITATIONS: The main limitation of this study is its retrospective design. In addition, the computation for the expected MP in pigs is based on arbitrary criteria. Different values of expected MP may change the absolute value of MP ratio but will not change the concept of the existence of an injury threshold.
conclusionsThe concept of MP
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.