Evidence map›Paper›PMID 39080140›Full record

ReviewArchives of dermatological research2024

A review of TEC family kinases and their inhibitors in the treatment of alopecia areata.

Yinglin An, Fan Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of dermatological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Targeting the BMX in cancer: molecular mechanisms and emerging therapeutic strategies.Journal of enzyme inhibition and medicinal chemistry · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yinglin An *School of Clinical Medicine, Peking University Health Science Center, Beijing, 100191, China.
Fan Zhang *Department of Dermatology and Venereology, Hair Medical Research Center, Beijing Jishuitan Hospital, Capital Medical University, No. 31 of Xinjiekou East Street, Xicheng District, Beijing, 100035, China. zhangfanzf63z@126.com.

Funding

2022 Capital Health Development Scientific Research Project 2022-2Z-2076
6 · The paper itself

Abstract

The TEC (tyrosine kinase expressed in hepatocellular carcinoma) family kinases, an important class of protein kinases, play key roles in cell signaling and immune regulation. In this review, the association between the pathogenesis of alopecia areata and the structure and regulatory mechanisms of TEC family kinases in normal physiological processes, is explored. Furthermore, the potential clinical applications of TEC kinases and their inhibitors are highlighted by summarizing current insights into their mechanisms of action, clinical applications, and recent advancements in TEC kinase inhibitor research.

Indexed as

Alopecia AreataProtein Kinase InhibitorsProtein-Tyrosine KinasesSignal TransductionAnimalsHumansProtein Kinase InhibitorsProtein-Tyrosine KinasesTec protein-tyrosine kinaseAlopecia areataBTKITKTEC family kinasesTEC kinase inhibitors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.