Evidence map›Paper›PMID 39080029›Full record

SynthesisSkeletal radiology2025

Yield and clinical impact of image-guided bone biopsy in osteomyelitis of the appendicular skeleton: a systematic review and meta-analysis.

Karen Smayra, Shahid Miangul, Maria M Witkowiak, Linn K M Persson, Emily E Lugard, Maamoun Adra, Nathanael Q E Yap, Jake Ball, Hayato Nakanishi, Christian A Than and 1 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Karen SmayraSt George's University of London, London, SW17 0RE, UK.
Shahid MiangulSt George's University of London, London, SW17 0RE, UK.
Maria M WitkowiakUniversity of Nicosia Medical School, University of Nicosia, 2417, Nicosia, Cyprus.
Linn K M PerssonUniversity of Nicosia Medical School, University of Nicosia, 2417, Nicosia, Cyprus.
Emily E LugardSt George's University of London, London, SW17 0RE, UK.
Maamoun AdraSt George's University of London, London, SW17 0RE, UK.
Nathanael Q E YapSt George's University of London, London, SW17 0RE, UK.
Jake BallDepartment of Medical Imaging, John Hunter Hospital, Newcastle, Australia.
Hayato NakanishiSt George's University of London, London, SW17 0RE, UK.
Christian A ThanSt George's University of London, London, SW17 0RE, UK. c.than@uq.edu.au.
Michael KhooDepartment of Radiology, Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the yield and clinical impact of image-guided bone biopsy for osteomyelitis of the appendicular skeleton. MATERIALS AND

methodsA literature search of several databases was conducted from inception to August 2023. Eligible studies reported patients who underwent image-guided bone biopsy for investigation of osteomyelitis of the appendicular skeleton. The pooled proportions were analyzed using a random-effects model. This review was registered in PROSPERO (CRD42023466419).

resultsFrom 370 initial studies screened, eight met the eligibility criteria, with a total of 700 patients. The pooled technical success rate was 99.6% (95% CI: 0.992, 1.001; I

conclusionFor patients under investigation of osteomyelitis of the appendicular skeleton, image-guided bone biopsy demonstrates a good rate of technical success. Additional studies may provide further support for the use of image-guided bone biopsy in this population. Image-guided bone biopsy results lead to change in antibiotics therapy in a portion of patients with suspected osteomyelitis suggesting its potential utility in select patients.

Indexed as

Image-Guided BiopsyOsteomyelitisHumansAppendicular skeletonBiopsyImage-guidedOsteomyelitis

Identifiers

PMID39080029
PMCPMC11769862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.