Evidence map›Paper›PMID 39079888›Full record

ArticleBMJ mental health2024

Potential dopaminergic deficit in patients with geriatric psychiatric disorders as revealed by DAT-SPECT: a cross-sectional study.

Shintaro Takenoshita, Seishi Terada, Katsuhide Kojima, Naoto Nishikawa, Tomoko Miki, Osamu Yokota, Masaki Fujiwara, Manabu Takaki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shintaro TakenoshitaDepartment of Neuropsychiatry, Okayama University Hospital, Okayama, Japan s.takenoshita@okayama-u.ac.jp.ORCID http://orcid.org/0000-0002-1483-7122
Seishi TeradaDepartment of Neuropsychiatry, Okayama University Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Katsuhide KojimaDepartment of Radiology, Okayama University Hospital, Okayama, Japan.
Naoto NishikawaDepartment of Neuropsychiatry, Okayama University Hospital, Okayama, Japan.
Tomoko MikiDepartment of Neuropsychiatry, Okayama University Hospital, Okayama, Japan.
Osamu YokotaDepartment of Neuropsychiatry, Okayama University Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Masaki FujiwaraDepartment of Neuropsychiatry, Okayama University Hospital, Okayama, Japan.
Manabu TakakiDepartment of Neuropsychiatry, Okayama University Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been reported that patients with geriatric psychiatric disorders include many cases of the prodromal stages of neurodegenerative diseases. Abnormal

methodsThe design is a cross-sectional study. Clinical findings of 61 inpatients aged 60 years or older who underwent DAT-SPECT and had been diagnosed with psychiatric disorders, but not neurodegenerative disease or dementia were analysed.

results36 of 61 (59%) had abnormal results on DAT-SPECT. 54 of 61 patients who had DAT-SPECT (89%) had undergone

conclusionPatients with geriatric psychiatric disorders include many cases showing abnormalities on DAT-SPECT. It is suggested that these cases are at high risk of developing neurodegenerative diseases characterised by a dopaminergic deficit. It is possible that patients with geriatric psychiatric disorders with abnormal findings on DAT-SPECT tend to show abnormalities on DAT-SPECT first rather than on

Indexed as

Dopamine Plasma Membrane Transport ProteinsMental DisordersTomography, Emission-Computed, Single-PhotonAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedDopamine Plasma Membrane Transport ProteinsCross-Sectional StudiesDelirium & cognitive disordersDepression & mood disorders

Identifiers

PMID39079888
PMCPMC11293386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.