ArticleUltrasonics sonochemistry2024
Comparison, optimization and antioxidant activity of ultrasound-assisted natural deep eutectic solvents extraction and traditional method: A greener route for extraction of flavonoid from Moringa oleifera Lam. leaves.
Article in Ultrasonics sonochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Ultrasound-assisted deep eutectic solvent extraction and macroporous resin enrichment of polyphenols from Cortex Mori: Screening of tyrosinase inhibitors via affinity ultrafiltration-LC-MS and molecular docking.Ultrasonics sonochemistry · 2026Article
- Ultrasound-assisted natural deep eutectic solvent for the extraction of flavonoids from hawk tea: COSMO-RS screening, optimization, andFood chemistry: X · 2026Article
- A Review ofFoods (Basel, Switzerland) · 2026Review
- Extraction and Recovery of Flavonoids from Tartary Buckwheat Using Deep Eutectic Solvents.Molecules (Basel, Switzerland) · 2026Article
- Optimization of ultrasound-assisted extraction of Sargassum polycystum for antitumor activity: Multi-objective optimization and mechanistic insights.Ultrasonics sonochemistry · 2026Article
- Ultrasound-assisted extraction of flavonoids from Cercis chinensis flowers using deep eutectic solvents: optimization, characterization, kinetics and bioactivity.Ultrasonics sonochemistry · 2026Article
- Phytochemical composition, in vitro antioxidant and antibacterial activities of Dorstenia barnimiana Schweinf leaf extracts.BMC complementary medicine and therapies · 2026Article
- Metabolomics analysis of antioxidant and lipid-lowering activities, colonic fermentation properties of quinoa bran polyphenol extract during in vitro digestion.NPJ science of food · 2025Article
- Ultrasound-Assisted Green Natural Deep Eutectic Solvent Extraction of Flavonoids from Wild Blueberry: Process Optimization, Composition Identification, and Antioxidant Activity.Foods (Basel, Switzerland) · 2025Article
- Deep Eutectic Solvent-Based Ultrasound-Assisted Extraction of Flavonoids fromFoods (Basel, Switzerland) · 2025Article
- Antibacterial and Antitumoral Potentials of Phytosynthesized Silver/Silver Oxide Nanoparticles Using Tomato Flower Waste.International journal of molecular sciences · 2024Article
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10 authors.
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Abstract
To develop an environmentally sustainable and efficient extraction method for flavonoids from Moringa oleifera Lam. (M. oleifera) leaves, natural deep eutectic solvents (NADES) with ultrasound-assisted extraction was utilized in this study. After optimization of extraction parameters of NADES, including ultrasonic power, ultrasonic time, and liquid-solid ratio, the extraction yield of ultrasound-assisted NADES (UAN) composed of betaine and urea (Bet-Urea) reached 54.69 ± 0.19 mg RE/g DW, which made a 1.7-fold increase compared to traditional ultrasound-assisted traditional solvent (UATS). UPLC-Q Exactive/MS analysis revealed that M. oleifera leaves flavonoids (MOLF) was mainly composed of Quercetin 3-β-D-glucoside, Rutin, Kaempferol-3-O-glucoside, Vitexin and Quercetin. Furthermore, the COSMO-RS model was employed to verify the optimal compatibility of solubility and activity coefficient between Bet-Urea and the five primary flavonoids in MOLF. In vitro antioxidant assays verified that MOLF extracted by UAN exhibited superior antioxidant activity compared to MOLF extracted by UATS. Overall, the devised process not only augmented the extraction yield of MOLF but also effectively preserved the bioactive compounds, thus promoting the utilization of green extraction solvents in the food industry.
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