SynthesisClinical oral investigations2024
Effectiveness of desensitizing toothpastes in reducing tooth sensitivity after tooth bleaching: a systematic review.
Synthesis in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions for bleaching-induced tooth sensitivity: an umbrella review.Frontiers in oral health · 2026Pooled it
- Efficacy and safety of low-concentration whitestrips for extrinsic tooth discoloration: a randomized controlled trial.Frontiers in oral health · 2026Trial
- Evaluation of tooth sensitivity and whitening effects of tooth whitening agents containing calcium, hydroxyapatite and fluoride.Odontology · 2026Article
- Real-Time Assessment of Dentinal Fluid Flow Reduction by Desensitising Agents Using Subnanolitre Flow Measuring System.International dental journal · 2026Article
- Assessment of dentinal fluid flow reduction following simulated brushing with desensitizing toothpastes using sub-nanoliter fluid flow measurement system.BMC oral health · 2026Article
- In-office tooth bleaching protocols: an umbrella review of systematic reviews and meta-analyses on whitening efficacy and tooth sensitivity.The Saudi dental journal · 2026Review
- Clinical myths in dental bleaching: an evidence-based structured narrative review.Brazilian oral research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effectiveness of desensitizing toothpastes in reducing post-bleaching tooth sensitivity. MATERIALS AND
methodsA systematic review of randomized clinical trials was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Electronic searches were conducted in the PubMed/MEDLINE, Scopus, Web of Science, The Cochrane Library and Embase databases, using the following terms: (dentifrices OR toothpaste) AND (sensitive OR sensitivity OR dental sensitivity) AND (dental bleaching OR tooth bleaching OR dental whitening OR tooth whitening).
resultsFive studies involving 387 individuals undergoing in-office or at-home teeth bleaching were reviewed. Desensitizing toothpastes reduced sensitivity effectively after home bleaching with 22% carbamide peroxide and single-session in-office bleaching with 35% hydrogen peroxide. However, they were ineffective for home bleaching with 16% carbamide peroxide and in-office bleaching across two sessions with 35% or 38% hydrogen peroxide.
conclusionDesensitizing toothpastes are effective for home bleaching with high concentration carbamide peroxide and single-session in-office bleaching with highly concentrated hydrogen peroxide, but ineffective for home bleaching with low concentration carbamide peroxide and two-session in-office bleaching with concentrated hydrogen peroxide.
Indexed as
Identifiers
39078468What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.