Evidence map›Paper›PMID 39078452›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2025

Opioid-related deaths in Northern Ontario in the early COVID-19 pandemic period.

Alexandra Nunn, Amanda M Perri, Hilary Gordon, John P D Harding, C K Jennifer Loo, John Tuinema

Abstract read
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Geographical narcissism and Ontario's opioid crisis.Canadian journal of public health = Revue canadienne de sante publique · 2025
    Article
  3. Responding to the toxic drug crisis: Promising innovations, gaps, and calls to action.Canadian journal of public health = Revue canadienne de sante publique · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandra NunnAlgoma Public Health, Sault Ste. Marie, ON, Canada. alexandra.nunn@phac-aspc.gc.ca.ORCID 0000-0002-0736-9316
Amanda M PerriAlgoma Public Health, Sault Ste. Marie, ON, Canada.ORCID 0000-0001-9674-6592
Hilary GordonAlgoma Public Health, Sault Ste. Marie, ON, Canada.
John P D HardingAlgoma Public Health, Sault Ste. Marie, ON, Canada.
C K Jennifer LooAlgoma Public Health, Sault Ste. Marie, ON, Canada.
John TuinemaAlgoma Public Health, Sault Ste. Marie, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn the first year of pandemic measures, opioid-related deaths across Ontario's (ON) 34 public health units (PHUs) increased by 60%. Death rates for all seven Northern ON PHUs were above the provincial average. This study describes and compares factors surrounding opioid-related deaths before and after pandemic measures were introduced, for Northern ON compared to the rest of ON.

methodsAggregate data were provided for Northern ON and the rest of the province by the Office of the Chief Coroner/Ontario Forensic Pathology Services. Opioid-related deaths were cohorted by date of death for the year before and after pandemic measures were introduced on March 16, 2020. Chi-square tests were used to compare between cohorts and geographies to determine significant differences for each variable, and for dichotomized levels within variables. P-values < 0.05 were considered statistically significant a priori.

resultsIn Northern ON, the number of opioid-related deaths approximately doubled from the pre-pandemic cohort (n = 185) to the early pandemic cohort (n = 365). Compared to the rest of ON, higher proportions of deaths occurred in Northern ON among individuals who lived and died in private residences, among women (although the majority of decedents were male) and among individuals employed in mining, quarrying, and oil and gas industries. Compared to the pre-pandemic year, in Northern ON, higher proportions of opioid-related deaths involved fentanyl and stimulants as direct contributors, and the majority involved evidence of inhaled drugs.

conclusionDifferences between the circumstances of death in Northern ON and in the rest of ON suggest opportunities to tailor interventions.

Indexed as

Analgesics, OpioidCOVID-19Opiate OverdoseOpioid-Related DisordersAdolescentAdultAgedDrug OverdoseFemaleHumansMaleMiddle AgedOntarioPandemicsYoung AdultAnalgesics, OpioidDrug overdoseDrug usersOpioid epidemicPublic healthSocial determinants of health

Identifiers

PMID39078452
PMCPMC12380652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.