Evidence map›Paper›PMID 39078038›Full record

Trial reportThe British journal of psychiatry : the journal of mental science2024

LSD-assisted therapy in patients with anxiety: open-label prospective 12-month follow-up.

Friederike Holze, Peter Gasser, Felix Müller, Manuel Strebel, Matthias E Liechti

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in The British journal of psychiatry : the journal of mental science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Acute and post-acute neurobehavioral responses to lysergic acid diethylamide in healthy subjects: a randomized controlled study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  13. Psychedelic-Assisted Therapy: Potential Benefits and Challenges in Mental Health Treatment.Medical science monitor : international medical journal of experimental and clinical research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Friederike HolzeClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland.ORCID https://orcid.org/0000-0003-3143-1519
Peter GasserClinic Dr Peter Gasser, Solothurn, Switzerland.
Felix MüllerPsychiatric University Hospital, University of Basel, Switzerland.
Manuel StrebelClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland.
Matthias E LiechtiClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland.ORCID https://orcid.org/0000-0002-1765-9659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnxiety disorders are a major public health burden with limited treatment options.

aimsWe investigated the long-term safety and efficacy of lysergic acid diethylamide (LSD)-assisted therapy in patients with anxiety with or without life-threatening illness.

methodThis study was an

resultsParticipants reported a sustained reduction of STAI-G scores compared with baseline (least square means (95% CI) = -21.6 (-32.7, -10.4),

conclusionsPatients reported sustained long-term effects of LSD-assisted therapy for anxiety.

Indexed as

Anxiety DisordersHallucinogensLysergic Acid DiethylamideAdultCross-Over StudiesDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesPsychiatric Status Rating ScalesTreatment OutcomeYoung AdultHallucinogensLysergic Acid DiethylamideanxietydepressionLSDpsychedelicsRCT

Identifiers

PMID39078038
PMCPMC11536188

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.