Evidence map›Paper›PMID 39077624›Full record

ReviewJTO clinical and research reports2024

Pathophysiology and Management of Chest Wall Pain after Surgical and Non-Surgical Local Therapies for Lung Cancer.

John Nikitas, Jane Yanagawa, Sandra Sacks, Edward K Hui, Alan Lee, Jie Deng, Fereidoun Abtin, Robert Suh, Jay M Lee, Paul Toste and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JTO clinical and research reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

John NikitasDepartment of Radiation Oncology, University of California, Los Angeles, Los Angeles, California.
Jane YanagawaDivision of Thoracic Surgery, University of California, Los Angeles, Los Angeles, California.
Sandra SacksDepartment of Anesthesiology, University of California, Los Angeles, Los Angeles, California.
Edward K HuiCenter for East-West Medicine, University of California, Los Angeles, Los Angeles, California.
Alan LeeDepartment of Radiation Oncology, University of California, Los Angeles, Los Angeles, California.
Jie DengDepartment of Radiation Oncology, University of California, Los Angeles, Los Angeles, California.
Fereidoun AbtinThoracic Imaging and Intervention, Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, California.
Robert SuhThoracic Imaging and Intervention, Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, California.
Jay M LeeDivision of Thoracic Surgery, University of California, Los Angeles, Los Angeles, California.
Paul TosteDivision of Thoracic Surgery, University of California, Los Angeles, Los Angeles, California.
Bryan M BurtDivision of Thoracic Surgery, University of California, Los Angeles, Los Angeles, California.
Sha'Shonda L RevelsDivision of Thoracic Surgery, University of California, Los Angeles, Los Angeles, California.
Robert B CameronDivision of Thoracic Surgery, University of California, Los Angeles, Los Angeles, California.
Drew MoghanakiDepartment of Radiation Oncology, University of California, Los Angeles, Los Angeles, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chest wall pain syndromes can emerge following local therapies for lung cancer and can adversely affect patients' quality-of-life. This can occur after lung surgery, radiation therapy, or percutaneous image-guided thermal ablation. This review describes the multifactorial pathophysiology of chest wall pain syndromes that develop following surgical and non-surgical local therapies for lung cancer and summarizes evidence-based management strategies for inflammatory, neuropathic, myofascial, and osseous pain. It discusses a step-wise approach to treating chest wall pain that begins with non-opioid oral analgesics and includes additional pharmacologic treatments as clinically indicated, such as anticonvulsants, serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants, and various topical treatments. For myofascial pain, physical medicine techniques, such as acupuncture, trigger point injections, deep tissue massage, and intercostal myofascial release can also offer pain relief. For severe or refractory cases, opioid analgesics, intercostal nerve blocks, or intercostal nerve ablations may be indicated. Fortunately, palliation of treatment-related chest wall pain syndromes can be managed by most clinical providers, regardless of the type of local therapy utilized for a patient's lung cancer treatment. In cases where a patient's pain fails to respond to initial medical management, clinicians can consider referring to a pain specialist who can tailor a more specific pharmacologic approach or perform a procedural intervention to relieve pain.

Indexed as

Chest wall painImage guided thermal ablationLung cancerLung surgeryRadiation therapyThoracotomy

Identifiers

PMID39077624
PMCPMC11284817

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.