Evidence map›Paper›PMID 39077524›Full record

ArticleReviews in cardiovascular medicine2023

Clinical Outcomes of Cryo Nerve Ablation Technique for Pain Management: An Exploratory Study in Patients Undergoing Left Thoracotomy Coronary Artery Bypass Grafting.

Aleksander Dokollari, Serge Sicouri, Ozgun Erten, Basel Ramlawi, Matteo Cameli, Giulia Elena Mandoli, Beatrice Bacchi, Francesco Cabrucci, Francis P Sutter, Stephanie Kjelstrom and 5 more

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aleksander DokollariDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA 3450, USA.
Serge SicouriDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA 3450, USA.
Ozgun ErtenDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA 3450, USA.
Basel RamlawiDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA 3450, USA.
Matteo CameliDepartment of Cardiology, Le Scotte Hospital, University of Siena, 53100 Siena, Italy.
Giulia Elena MandoliDepartment of Cardiology, Le Scotte Hospital, University of Siena, 53100 Siena, Italy.
Beatrice BacchiF.U. of Cardiac Surgery, Department of Experimental and Clinical Medicine - University of Florence, 50134 Firenze, Italy.
Francesco CabrucciF.U. of Cardiac Surgery, Department of Experimental and Clinical Medicine - University of Florence, 50134 Firenze, Italy.
Francis P SutterDepartment of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, PA 3450, USA.
Stephanie KjelstromDepartment of Cardiac Surgery, Population Health, Lankenau Institute for Medical Research, Wynnewood, PA 3450, USA.
Georgia MontoneDepartment of Cardiac Surgery, Population Health, Lankenau Institute for Medical Research, Wynnewood, PA 3450, USA.
Noah SicouriDepartment of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, PA 3450, USA.
Leila HosseinianDepartment of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, PA 3450, USA.
Massimo BonacchiF.U. of Cardiac Surgery, Department of Experimental and Clinical Medicine - University of Florence, 50134 Firenze, Italy.
Gianluca TorregrossaDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA 3450, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To investigate the impact of Cryo Nerve Block with cryoICE™ device utilization, on post-operative pain in patients undergoing isolated coronary artery bypass grafting (CABG) through left thoracotomy. Methods: All consecutive patients undergoing isolated CABG through left thoracotomy between July 2021 and July 2022 from a single surgeon were included in the study. Patients using the cryoICE™ device for nerve block were compared for baseline demographics and pre-operative characteristics with those that did not use the cryoICE™ device. A propensity-adjusted analysis was used to compare the two groups. The primary outcome was degree of incisional pain and numbness. Results: A total of 103 patients underwent isolated CABG through left thoracotomy. After matching, the cryoICE™ device was used for nerve block in 60 patients while the control group included 43 patients. Mean follow-up was 5.7 months. The cryoICE™ device group had a mean value of incisional pain at hospital discharge was 1.5 (scale 0-10) while at follow-up was 0.69 (scale 0-10). Mean values of skin numbness at hospital discharge were 1 (scale 0-10) and 0.57 (scale 0-10) at follow-up. After univariate analysis comparison of cryoICE™ device group (60 patients) versus non-cryoICE™ device group (43 patients), the total in-hospital morphine use was 49% lower in the cryoICE™ versus the non-cryoICE™ cohort (73.8 + 79.37 mg vs 144.1 + 118.99 mg). Conclusions: Good clinical outcomes were observed in patients undergoing isolated left thoracotomy CABG with cryoICE™ utilization, including a very low incidence of post-operative pain, numbness, and hypersensitivity for all comers.

Indexed as

cryoICE™Cryo Nerve Blocknumbnessopioidspainsensitivity

Identifiers

PMID39077524
PMCPMC11264104

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.