Evidence map›Paper›PMID 39077487›Full record

ReviewReviews in cardiovascular medicine2023

Novel Pathophysiological, Diagnostic and Therapeutic Concepts in Acute and Recurrent Pericarditis.

Aldo Bonaventura, Georgia K Thomas, Michele Golino, Adolfo Gabriele Mauro, Alessandra Vecchié, Marco Giuseppe Del Buono, Stefano Toldo, Nicola Potere, Antonio Abbate

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aldo BonaventuraS.C. Medicina Generale 1, Medical Center, Ospedale di Circolo e Fondazione Macchi, ASST Sette Laghi, 21100 Varese, Italy.
Georgia K ThomasVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23220, USA.
Michele GolinoVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23220, USA.
Adolfo Gabriele MauroVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23220, USA.
Alessandra VecchiéS.C. Medicina Generale 1, Medical Center, Ospedale di Circolo e Fondazione Macchi, ASST Sette Laghi, 21100 Varese, Italy.
Marco Giuseppe Del BuonoDepartment of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00161 Rome, Italy.
Stefano ToldoVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23220, USA.
Nicola PotereDepartment of Innovative Technologies in Medicine and Dentistry, "G. D'Annunzio" University, 66100 Chieti, Italy.
Antonio AbbateDepartment of Medicine, Division of Cardiovascular Medicine and Robert M. Berne Cardiovascular Research Center, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pericarditis is the most frequent pericardial disease characterized by inflammation of the pericardial layers resulting in pain, dyspnea and fatigue. Often limited to an isolated event, up to 30% of patients experience one or more recurrences. There is limited knowledge about the pathophysiology of this disease, possibly due to the limited availability of animal models. More recently, following seminal clinical trials with colchicine and interleukin-1 (IL-1) blockers and a novel murine model of acute pericarditis using zymosan A, it has become clear that the NLRP3 (NACHT, leucine-rich repeat, and pyrin domain-containing protein 3) inflammasome/IL-1

Indexed as

acute pericarditisanakinraIL-1αIL-1βinflammationNLRP3 inflammasomerecurrent pericarditisrilonacept

Identifiers

PMID39077487
PMCPMC11264016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.