Evidence map›Paper›PMID 39077458›Full record

ArticleVeterinary world2024

Effects of house-cultivated edible bird's nest on immunoglobulin and cytokine release

Mel June Choong, Hemaniswarri Dewi Dewadas, Lay Cheng Lim, Sheela Devi Sukuru, Chee Hong Tan, Soon Keng Cheong, Yang Mooi Lim

Abstract read
In one paragraph

Article in Veterinary world, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mel June ChoongCentre for Cancer Research, M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Selangor, Malaysia.
Hemaniswarri Dewi DewadasCentre for Biomedical and Nutrition Research, Faculty of Science, Universiti Tunku Abdul Rahman, Jalan Universiti, Kampar, 31900, Perak, Malaysia.
Lay Cheng LimDepartment of Life Sciences, School of Pharmacy, International Medical University, 57000 Kuala Lumpur, Malaysia.
Sheela Devi SukuruDepartment of Nursing, M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Selangor, Malaysia.
Chee Hong TanInbit Biotech Sdn. Bhd., No. 8, Lorong University B, Seksyen 16, 46350 Petaling Jaya, Selangor, Malaysia.
Soon Keng CheongDepartment of Medicine, M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Selangor, Malaysia.
Yang Mooi LimCentre for Cancer Research, M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Selangor, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Edible bird's nest (EBN) is known as the "Caviar of the East" because of its high nutritional and medicinal values. Nevertheless, its effect on human immunity is yet to be explored. This study examined the effects of EBN's aqueous extract (EBNE) on human immunity through the modular immune Materials and Methods: One hundred twenty mL of full blood was obtained from four healthy human volunteers. The human immune system was simulated using an Results: IgE, IgA, and IgG3 levels were significantly raised by EBNE. These cytokines, including brain-derived neurotrophic factor, ciliary neurotrophic factor, glial cell line-derivative neurotrophic factor, insulin-like growth factor 1, and insulin-like growth factor binding protein 4, were generated. Conclusion: For the first time, this work uses a MIMIC model to illustrate the impact of EBNE on human immune response. This new understanding of EBN's immunoregulatory effect allows for further exploration of how EBN interacts with the human immune system.

Indexed as

cytokinesedible bird’s nestimmunoglobulinsmodular immune in vitro construct modelswiftlets

Identifiers

PMID39077458
PMCPMC11283608

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.