ArticleCureus2024
Malnutrition and Its Influence on Sepsis Outcomes in Elderly Patients.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Development and Validation of a Nomogram for Mortality Prediction in Septic Patients with Prolonged or Chronic Critical Illness.Diagnostics (Basel, Switzerland) · 2026Article
- Comparison of the predictive value of NUTRIC and modified NUTRIC scores for ICU mortality in patients with sepsis: a single-center prospective cohort study.Scientific reports · 2026Article
- Prognostic Value of Nutritional Risk Scores in Septic ICU Patients: A Survival Analysis Using mNUTRIC, PNI, and CONUT.Diagnostics (Basel, Switzerland) · 2026Article
- Hypoalbuminemia as a predictor of mortality in patients with acute cholangitis: A systematic review and meta-analysis.World journal of gastrointestinal pathophysiology · 2026Article
- Optimizing Clinical Nutrition Management for Elderly Hospitalized Patients: Current Practices and Insights.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Timing matters: a machine learning-driven comparison of community and hospital-onset sepsis.BMC medical informatics and decision making · 2026Article
- Development and validation of a nomogram for early nutritional risk stratification in elderly patients with pulmonary sepsis: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Sepsis in multimorbidity: a domain-based framework for systemic vulnerability and precision care.Frontiers in medicine · 2026Review
- Association between prognostic nutritional index and 90-day mortality in septic patients: a retrospective cohort study.BMC nutrition · 2025Article
- Article
- Association between NUTRIC score and ICU mortality in patients with sepsis: a prospective cohort study.Frontiers in nutrition · 2025Article
- Association between the serum albumin-creatinine ratio and 28-day intensive care unit mortality among patients with sepsis: a multicenter retrospective cohort study.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition is common among the elderly and has significant implications for hospitalization outcomes. This is particularly true for severe illnesses such as sepsis, given age-related physiological changes and comorbidities.
objectiveThis study examined how malnutrition affected hospitalization outcomes in older adults admitted for sepsis. MATERIALS &
methodsA prospective cohort study was conducted at Lady Reading Hospital in Peshawar, Pakistan, from January to December 2023, focusing on 390 sepsis patients aged 55 years and older. Data on clinical history, length of stay, mortality rates, comorbidities, and nutritional assessments were collected using standardized forms. After controlling for confounding variables, statistical analysis using SPSS version 23 (IBM Corp., Armonk, NY) examined the relationship between hospitalization outcomes and nutritional status.
resultsThe research included 390 elderly sepsis patients and showed significant variations in the demographics, comorbidities, and severity of disease between the well-nourished and malnourished groups. Malnourished patients had higher rates of ICU admission (52.82% vs. 29.23%), mechanical ventilation (45.13% vs. 16.41%), mortality (27.18% vs. 14.87%), and 30-day readmission (28.21% vs. 12.82%) as compared to the well-nourished group. They also had longer hospital stays (18.1 days vs. 12.6 days). Malnutrition significantly influenced outcomes, with multivariate analysis indicating it as a predictor of longer stays (β = 2.8, p < 0.001) and increased mortality risk (OR = 3.2, 95% CI: 1.9-5.4, p < 0.001).
conclusionMalnutrition significantly worsens outcomes for elderly sepsis patients, increasing ICU admissions, ventilation needs, mortality rates, and readmissions, emphasizing the need for proactive nutritional interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.