Evidence map›Paper›PMID 39077267›Full record

ArticleCureus2024

Effect of Dental Local Anesthetics on Reactive Oxygen Species: An In Vitro Study.

Hidetaka Kuroda, Shota Tsukimoto, Azuma Kosai, Noriko Komatsu, Takehito Ouchi, Maki Kimura, Aiji Sato-Boku, Ayaka Yoshida, Fumihiko Yoshino, Takahiro Abe and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hidetaka KurodaDepartment of Dental Anesthesiology, Kanagawa Dental University, Kanagawa, JPN.
Shota TsukimotoDepartment of Dental Anesthesiology, Kanagawa Dental University, Kanagawa, JPN.
Azuma KosaiDepartment of Oral and Maxillofacial Surgery, Kanagawa Dental University, Kanagawa, JPN.
Noriko KomatsuDepartment of Oral and Maxillofacial Surgery, Kanagawa Dental University, Kanagawa, JPN.
Takehito OuchiDepartment of Physiology, Tokyo Dental College, Tokyo, JPN.
Maki KimuraDepartment of Physiology, Tokyo Dental College, Tokyo, JPN.
Aiji Sato-BokuDepartment of Anesthesiology, Aichi Gakuin University, Nagoya, JPN.
Ayaka YoshidaDepartment of Liberal Arts Education, Kanagawa Dental University, Kanagawa, JPN.
Fumihiko YoshinoDepartment of Pharmacology, Kanagawa Dental University, Kanagawa, JPN.
Takahiro AbeDepartment of Oral and Maxillofacial Surgery, Kanagawa Dental University, Kanagawa, JPN.
Yoshiyuki ShibukawaDepartment of Physiology, Tokyo Dental College, Tokyo, JPN.
Takuro SanukiDepartment of Dental Anesthesiology, Kanagawa Dental University, Kanagawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Oxidative stress, an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, plays an important role in various dental diseases. Local anesthetics are frequently used in dentistry. The potential antioxidant activity of dental local anesthetics can contribute to dental practice. Therefore, this study aimed to investigate the ROS-scavenging activities of three commonly used dental local anesthetics, lidocaine, prilocaine, and articaine, focusing on their effects on hydroxyl radicals (HO

Indexed as

antioxidative effectsarticainehydroxyl radicallidocaineoxidative stressprilocainereactive oxygen speciessuperoxide anion

Identifiers

PMID39077267
PMCPMC11286320

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.