Evidence map›Paper›PMID 39077175›Full record

ArticleReviews in cardiovascular medicine2022

Bioelectrical Impedance Analysis as a Contemporary Biomarker of Obesity in Adults with Marfan- or Loeys-Dietz-Syndrome.

Sebastian Freilinger, Mathieu N Suleiman, Gert Bischoff, Peter Ewert, Annika Freiberger, Michael Huntgeburth, Ann-Sophie Kaemmerer, Judith Schopen, Christian Meierhofer, Nicole Nagdyman and 3 more

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sebastian FreilingerClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Mathieu N SuleimanDepartment of Cardiac Surgery, University Hospital Erlangen, Friedrich-Alexander-University, 91054 Erlangen, Germany.
Gert BischoffZentrum für Ernährungsmedizin und Prävention (ZEP), Krankenhaus Barmherzige Brüder München, 80639 Munich, Germany.
Peter EwertClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Annika FreibergerClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Michael HuntgeburthClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Ann-Sophie KaemmererDepartment of Cardiac Surgery, University Hospital Erlangen, Friedrich-Alexander-University, 91054 Erlangen, Germany.
Judith SchopenClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Christian MeierhoferClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Nicole NagdymanClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Harald KaemmererClinic for Congenital Heart Disease and Pediatric Cardiology, German Heart Centre Munich, Technical University Munich, 80636 Munich, Germany.
Michael WeyandDepartment of Cardiac Surgery, University Hospital Erlangen, Friedrich-Alexander-University, 91054 Erlangen, Germany.
Frank HarigDepartment of Cardiac Surgery, University Hospital Erlangen, Friedrich-Alexander-University, 91054 Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It is clinically widely overlooked that many patients with Marfan- (MFS) or Loeys-Dietz-Syndrome (LDS) are obese. While anthropometric routine parameters are not very suitable, the modern Bioelectrical Impedance Analysis (BIA) seems superior for the acquisition of reliable noninvasive assessment of body composition of patients. The aim of the study was to assess the body composition of patients with MFS/LDS by BIA in order to detect occult obesity, which may be a risk marker for aortic or vascular complications. Methods: In this exploratory cross-sectional study, 50 patients (66% female; mean age: 37.7 Results: The MFS/LDS collective was significantly different from an age-, sex-, and BMI-adjusted control in terms of body fat, percent cellularity, body cell mass, extra cellular mass/body cell mass index, and phase angle (all Conclusions: The fact that many patients with MFS or LDS are obese is widely unknown, although obesity may be associated with impaired vascular endothelial function and an increased risk of cardiovascular complications. Also, in patients with MFS/LDS, BIA allows a reliable assessment of the body composition beyond the normal anthropometric parameters, such as BMI. In the future, BIA-data possibly may be of particular importance for the assessment of the vascular risk of MFS/LDS patients, besides the aortic diameters.

Indexed as

adults with congenital heart diseasebioelectrical impedance analysisbody compositionLoeys-Dietz-SyndromeMarfan-Syndromeobesity

Identifiers

PMID39077175
PMCPMC11274033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.