ReviewScience in One Health2023
COVID-19 vaccine hesitancy worldwide and its associated factors: a systematic review and meta-analysis.
Review in Science in One Health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- COVID- 19 vaccine uptake and its determinants in Cameroon: a systematic review and meta-analysis (2021-2024).BMC infectious diseases · 2025Pooled it
- COVID-19 vaccine acceptance and hesitancy in Cameroon: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- COVID-19 risk perception, preventive behaviors, vaccination acceptance and hesitancy, and psychosocial status in liver transplant recipients.Frontiers in public health · 2026Article
- Vaccine-related misinformation and attitude toward COVID-19 vaccination in Japan.Frontiers in public health · 2026Article
- Establishing a Preparedness Program: Lessons From COVID-19 to Strengthen Global Strategies for Future Pandemics.Cureus · 2025Review
- Vaccine hesitancy and decision regret among nurses in oncology settings in Italy: a cluster-based profile analysis.Scientific reports · 2025Article
- Attitudes Towards the HPV Vaccine Among Oropharyngeal Cancer Patients in a Post-COVID World.Laryngoscope investigative otolaryngology · 2025Article
- The importance of political and religious affiliation in explaining county-level COVID-19 Vaccine Hesitancy.Health economics review · 2025Article
- Article
- Paranoia affected COVID-19 vaccine refusal by increasing beliefs in conspiracy theories and mistrust of science.Frontiers in psychology · 2025Article
- Celebrating three years ofScience in One Health · 2025Article
- Vaccine Hesitancy and Associated Factors Amongst Health Professionals: A Scoping Review of the Published Literature.Vaccines · 2024Article
- Online Media Use and COVID-19 Vaccination in Real-World Personal Networks: Quantitative Study.Journal of medical Internet research · 2024Article
- Effectiveness of an Infection Control Program Among the Ysleta del Sur Pueblo in Preventing COVID-19-Related Hospitalizations and Deaths.Pathogens (Basel, Switzerland) · 2024Article
- Article
- Article
- The global burden of disease attributable to preterm birth and low birth weight in 204 countries and territories from 1990 to 2019: An analysis of the Global Burden of Disease Study.Journal of global health · 2024Article
- Perceptions of Risk, Benefit and Trust - A Comparative Assessment Between Healthcare Workers and the General Public Towards 3 Medical Technologies.Risk management and healthcare policy · 2024Article
- Quantitative Synthesis of Factors Associated with COVID-19 Vaccine Acceptance and Vaccine Hesitancy in 185 Countries.Vaccines · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has taken a toll on humans, and the development of effective vaccines has been a promising tool to end the pandemic. However, for a vaccination program to be successful, a considerable proportion of the community must be vaccinated. Hence, public acceptance of coronavirus disease 2019 (COVID-19) vaccines has become the key to controlling the pandemic. Recent studies have shown vaccine hesitancy increasing over time. This systematic review aims to evaluate the COVID-19 vaccine hesitancy rate and related factors in different communities. Method: A comprehensive search was performed in MEDLINE (via PubMed), Scopus, and Web of Science from January 1, 2019 to January 31, 2022. All relevant descriptive and observational studies (cross-sectional and longitudinal) on vaccine hesitancy and acceptance were included in this systematic review. In the meta-analysis, odds ratio (OR) was used to assess the effects of population characteristics on vaccine hesitancy, and event rate (acceptance rate) was the effect measure for overall acceptance. Publication bias was assessed using the funnel plot, Egger's test, and trim-and-fill methods. Result: A total of 135 out of 6,417 studies were included after screening. A meta-analysis of 114 studies, including 849,911 participants, showed an overall acceptance rate of 63.1%. In addition, men, married individuals, educated people, those with a history of flu vaccination, those with higher income levels, those with comorbidities, and people living in urban areas were less hesitant. Conclusion: Increasing public awareness of the importance of COVID-19 vaccines in overcoming the pandemic is crucial. Being men, living in an urban region, being married or educated, having a history of influenza vaccination, having a higher level of income status, and having a history of comorbidities are associated with higher COVID-19 vaccine acceptance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.