SynthesisReviews in cardiovascular medicine2023
Association between Cardiovascular Diseases and Peri-Implantitis: A Systematic Review and Meta-Analysis.
Synthesis in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- A Comparative Bioinformatics Analysis of the Transcriptomic Profiles of Peri-Implantitis and Periodontitis and Their Common Signaling Pathways with Atherosclerosis.Current issues in molecular biology · 2026Article
- Assessment of Residual Bone Level Around Explanted Implants and Description of the Systemic and Local Characteristics. A Retrospective Study.Clinical oral implants research · 2025Article
- The Impact of Peri-Implant Diseases on the General Status of Patients with Cardiovascular Diseases: A Literature Review.Life (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A potential relationship between oral inflammation and cardiovascular disease has been proposed; however, the impact of cardiovascular disease on implant restoration remains unclear. This systematic review aims to assess the relationship between peri-implantitis and cardiovascular disease based on review of data obtained through observational studies. Materials and Methods: An extensive systematic literature search was performed using the PubMed/MEDLINE, Scopus, Web of Science and Cochrane Library databases. Studies published in English language up to June 2022 were conducted in accordance with PRISMA guidelines. These efforts identified 230 unique publications and, after selection, five studies were included in this meta-analysis. The Newcastle-Ottawa Scale table was used for literature quality assessment. A fixed-effect model was selected and RevMan software version 5.3 was used to identify the origin of the outcomes of the meta-analysis. Finally, results were reported through the PRISMA statement. Results: This meta-analysis found that in implant restoration the incidence of peri-implantitis in patients with cardiovascular disease was higher than those without cardiovascular disease (Risk ratio (RR) = 1.12; 95% CI: 1.02-1.23; z = 2.34; Conclusions: Based on current evidence, we conclude that the presence of cardiovascular disease increases the incidence of peri-implantitis. Registration: PROSPERO database (CRD42022353693).
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Registered trials
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