Evidence map›Paper›PMID 39076866›Full record

ReviewReviews in cardiovascular medicine2023

Transcatheter Edge-to-Edge Repair of Mitral Valve Regurgitation: Closing the Gap to Broaden the Coverage.

Hafiz Imran, Khansa Ahmad, Muhammad Baig, Islam Y Elgendy, Nasir Iqbal, Afshin Ehsan, Barry Sharaf, Paul Gordon, Marwan Saad

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hafiz ImranDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI 02903, USA.
Khansa AhmadDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI 02903, USA.
Muhammad BaigDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI 02903, USA.
Islam Y ElgendyDivision of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY 40536, USA.
Nasir IqbalDivision of Cardiovascular Medicine, Azra Naheed Medical College, 55150 Lahore, Pakistan.
Afshin EhsanLifespan Cardiovascular Institute, Providence, RI 02903, USA.
Barry SharafDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI 02903, USA.
Paul GordonDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI 02903, USA.
Marwan SaadDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI 02903, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter edge-to-edge repair of mitral valve (M-TEER) is reasonable consideration in symptomatic patients with severe degenerative mitral regurgitation (MR) who are at high or prohibitive risk of surgical repair or replacement. In symptomatic patients on maximally tolerated medical therapy with severe secondary MR from left ventricular systolic dysfunction, M-TEER is reasonable therapeutic option. Methods: In this review, we present a comprehensive overview of the most recent literature and considerations for M-TEER in patients excluded from key trials. These include patients with cardiogenic shock, acute ischemic MR, atrial functional MR, failed surgical mitral valve prosthesis and pulmonary hypertension. Conclusions: M-TEER is feasible and a reasonable alternative option for these patient populations with a significant clinical benefit. However, randomized clinical trials are needed to ascertain findings from these observational studies.

Indexed as

acute ischemic mitral regurgitationatrial mitral regurgitationmitral regurgitationtranscatheter edge-to-edge repair of mitral valve regurgitation

Identifiers

PMID39076866
PMCPMC11270398

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.