Evidence map›Paper›PMID 39076743›Full record

ReviewReviews in cardiovascular medicine2023

Athlete's Heart: A Cardiovascular Step-By-Step Multimodality Approach.

Stefano Palermi, Elena Cavarretta, Flavio D'Ascenzi, Silvia Castelletti, Fabrizio Ricci, Marco Vecchiato, Alessandro Serio, Luna Cavigli, Eduardo Bossone, Giuseppe Limongelli and 5 more

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Sporting Careers After ICD Implantation in Elite Athletes.Journal of cardiovascular development and disease · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Vademecum for the Physician Evaluating a Master Athlete.Current atherosclerosis reports · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Stefano PalermiPublic Health Department, University of Naples Federico II, 80131 Naples, Italy.
Elena CavarrettaDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.
Flavio D'AscenziDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Silvia CastellettiCardiology Department, Istituto Auxologico Italiano IRCCS, 20149 Milan, Italy.
Fabrizio RicciDepartment of Neuroscience, Imaging and Clinical Sciences, G.d'Annunzio University of Chieti-Pescara, 66100 Chieti, Italy.
Marco VecchiatoSports and Exercise Medicine Division, Department of Medicine, University of Padova, 35128 Padova, Italy.
Alessandro SerioPublic Health Department, University of Naples Federico II, 80131 Naples, Italy.
Luna CavigliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Eduardo BossoneDivision of Cardiology, AORN A Cardarelli Hospital, 80131 Naples, Italy.
Giuseppe LimongelliDepartment of Translational Medical Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Alessandro BiffiMed-Ex, Medicine & Exercise, Medical Partner Scuderia Ferrari, 00187 Rome, Italy.
Emanuele MondaDepartment of Translational Medical Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Andre La GercheClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
Aaron BaggishCardiovascular Performance Program, Massachusetts General Hospital, Boston, MA 02114, USA.
Antonello D'AndreaUnit of Cardiology and Intensive Coronary Care, Umberto I Hospital, 84014 Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"Athlete's heart" is a spectrum of morphological, functional, and regulatory changes that occur in people who practice regular and long-term intense physical activity. The morphological characteristics of the athlete's heart may overlap with some structural and electrical cardiac diseases that may predispose to sudden cardiac death, including inherited and acquired cardiomyopathies, aortopathies and channelopathies. Overdiagnosis should be avoided, while an early identification of underlying cardiac life-threatening disorders is essential to reduce the potential for sudden cardiac death. A step-by-step multimodality approach, including a first-line evaluation with personal and family history, clinical evaluation, 12-lead resting electrocardiography (ECG), followed by second and third-line investigations, as appropriate, including exercise testing, resting and exercise echocardiography, 24-hour ECG Holter monitoring, cardiac magnetic resonance, computed tomography, nuclear scintigraphy, or genetic testing, can be determinant to differentiate between extreme physiology adaptations and cardiac pathology. In this context, cardiovascular imaging plays a key role in detecting structural abnormalities in athletes who fall into the grey zone between physiological adaptations and a covert or early phenotype of cardiovascular disease.

Indexed as

athlete's heartcardiovascular imagingpre-participation screeningsports activitysports cardiologysudden cardiac death

Identifiers

PMID39076743
PMCPMC11273059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.